Effects of extracellular matrix viscoelasticity on cellular . . . Substantial research over the past two decades has established that extracellular matrix (ECM) elasticity, or stiffness, affects fundamental cellular processes, including spreading, growth, proliferation, migration, differentiation and organoid formation
Viscoelasticity of ECM and cells—origin, measurement and . . . Future research should focus on understanding the impact of cell viscoelasticity on the degradation, reorganization, and sedimentation of the extracellular matrix, particularly in relation to the ECM's degradation and reorganization
Extracellular Matrix Viscoelasticity: A Dynamic Regulator of . . . The extracellular matrix (ECM) is a three-dimensional network of polysaccharides and proteins that provides biochemical signals and structural rigidity to cells In addition to structural support, the ECM provides dynamic mechanical properties such as viscoelasticity Scientifically, viscoelasticity is the time-dependent response of materials under stress Due to the viscoelastic behavior of
Viscosity regulates cell spreading and cell‐extracellular . . . Changes in viscosity have been recently suggested as a regulator of cell locomotion These novel studies focus on cell migration and spreading on glass substrates and through microchannels, and it remains a question whether viscosity impacts the cellular remodeling of extracellular matrices (ECMs)
The impact of extracellular matrix viscoelasticity on . . . Significant research over the past two decades has established that extracellular matrix (ECM) elasticity, or stiffness, impacts fundamental cell processes including spreading, growth, proliferation, migration, differentiation, and organoid formation