Semaglutide - ALZFORUM Semaglutide is a synthetic, long-acting analog of glucagon-like peptide-1, used to treat diabetes Ozempic TM is a once-per-week injection formulation, while Rybelsus TM is is a daily pill Rybelsus TM was approved by the U S FDA in September 2019 as the first GLP-1 analog that does not need to be injected
The Discovery and Development of Liraglutide and Semaglutide . . . - ALZFORUM The Discovery and Development of Liraglutide and Semaglutide Front Endocrinol (Lausanne) 2019;10:155 Epub 2019 Apr 12 PubMed Recommends Please login to recommend the paper Comments No Available Comments Make a Comment To make a comment you must login or register
Liraglutide - ALZFORUM Diabetes, high blood sugar, and insulin resistance are all associated with dementia In Alzheimer’s disease, there is evidence for insulin resistance in the brain Thus, there has been much interest in testing liraglutide and other GLP-1 analogs, such as exendin-4, semaglutide, and lixisenatide, as potential therapeutics for AD
NT-0796 | ALZFORUM In diet-induced obesity in these mice, NT-0796 caused weight loss as potently as did the GLP1 inhibitor semaglutide, and improved markers of cardiovascular risk (Thornton et al , 2024) It did not cause weight loss in non-obese mice Findings
Semaglutide is Neuroprotective and Reduces α-Synuclein Levels in the . . . Semaglutide is Neuroprotective and Reduces α-Synuclein Levels in the Chronic MPTP Mouse Model of Parkinson's Disease J Parkinsons Dis 2019;9(1):157-171 PubMed Recommends Please login to recommend the paper Comments No Available Comments Make a Comment To make a comment you must login or register
Semaglutide as a possible therapy for healthy aging: Targeting the . . . Semaglutide as a possible therapy for healthy aging: Targeting the hallmarks of aging Ageing Res Rev 2024 Dec;102:102582 Epub 2024 Nov 14 PubMed Recommends Please login to recommend the paper Comments No Available Comments Make a Comment To make a comment you must login or register
Novel LC-MS MS analysis of the GLP-1 analog semaglutide with its . . . Novel LC-MS MS analysis of the GLP-1 analog semaglutide with its application to pharmacokinetics and brain distribution studies in rats J Chromatogr B Analyt Technol Biomed Life Sci 2023 Apr 15;1221:123688 Epub 2023 Mar 22 PubMed Recommends Please login to recommend the paper Comments No Available Comments Make a Comment
Semaglutide Attenuates Anxious and Depressive-Like Behaviors and . . . Semaglutide Attenuates Anxious and Depressive-Like Behaviors and Reverses the Cognitive Impairment in a Type 2 Diabetes Mellitus Mouse Model Via the Microbiota-Gut-Brain Axis J Neuroimmune Pharmacol 2024 Jul 23;19(1):36