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  • Medications to Avoid if You Have an MTHFR Mutation
    With the right diet and supplements, it's entirely possible to optimize methylation in your body and reduce the risk of MTHFR-related health issues At the same time, you should be aware that certain medications may negatively impact an MTHFR mutation
  • Type 2 Diabetes Debate: Metformin Versus GLP-1 Receptor Agonists
    He reported that the only drug that might be preferred over metformin as initial monotherapy for type 2 diabetes would be a drug that is more potent, provides a longer duration of effectiveness, or improves long-term microvascular or macrovascular complications significantly
  • Comparing Glucagon‐like peptide‐1 receptor agonists versus metformin in . . .
    Compared to metformin, GLP‐1 RA was associated with greater HbA1c reduction (prediabetes: −2 59 mmol mol 95% CI: −3 10 to −2 09, diabetes: −3 79 mmol mol, 95% CI: −5 28 to −2 30) GLP‐1 RA was associated with a reduced risk of additional glucose‐lowering medication, achieving better glycated hemoglobin control overall
  • Metformin and MTHFR: Potential for Decreased Methylation
    MTHFR C677T variants typically have increased levels of homocysteine – if untreated The combination of MTHFR C677T and Metformin reduces one’s ability to adequately methylate Supplement with vitamin B12 and methylfolate if using Metformin and or having the C677T MTHFR variant
  • Is Metformin a GLP-1? Key Insights on Type 2 Diabetes Meds
    Metformin and GLP-1 receptor agonists are both used to manage type 2 diabetes, but they work in distinct ways Understanding their differences helps patients and healthcare providers make informed treatment decisions
  • MTHFR and Metformin: The Genetic Link That Could Change Your Treatment
    Research into the MTHFR gene's role in metabolizing medications is unveiling a crucial link between genetic variations and the efficacy of Metformin Understanding this connection could revolutionize diabetes treatment, tailoring therapies for better outcomes
  • Blood Sugar, Hashimoto’s, Ozempic, Metformin and Berberine
    Low folate levels may also be associated with the MTHFR gene variation, which you can read more about in this article You can work with your doctor to get your folate levels tested, or self-order through Ulta Lab Tests
  • Are GLP-1s and SGLT2s replacements for Metformin or in addition to . . .
    However, starting with an SGLT2 inhibitor or a GLP-1 RA in an individual who is intolerant to metformin (primarily diarrhea) is a good choice, and even in the future we may see large diabetes organizations recommending these two classes as first line therapy once they get less expensive
  • 8 Metformin Alternatives to Consider for Type 2 Diabetes - GoodRx
    Metformin is a first-choice medication for treating Type 2 diabetes But if you can’t tolerate metformin or it’s not doing enough to help you reach your diabetes goals, you may need an alternative
  • Which GLP-1 Medication Is Right For Me? | Wisp
    Glucagon-like peptide-1 (GLP-1) receptor agonist is a class of drugs that mimic a hormone made in your gut–also called GLP-1 These drugs help regulate your blood sugar, reduce your appetite, and slow down your digestion so you feel full for longer (1)





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