Table 1 Age-specific PSA thresholds for people with possible . . . greater emphasis on a patient centred approach New PSA ranges will be as follows: Table 1 Age-specific PSA thresholds for people with possible symptoms of prostate cancer Age (years) PSA threshold in mcg L Below 40 Use clinical judgement 40 to 49 2 5 50 to 59 3 5 60 to 69 4 5 70 to 79 6 5 Above 79 Use clinical judgement
What Is a Normal PSA Level by Age? High Level and Chart PSA levels can be detected in the blood, urine, or semen Blood PSA testing is used as a screening test for prostate cancer Prostate-specific antigen (PSA) levels by age remain the same across most populations A PSA level above 4 0 ng mL in any age group must be investigated
PSA blood test - NHS guidelines and Prostate Cancer UK’s risk . . . Furthermore, whilst the NHS advice acknowledges that “most research into PSA testing has been among men aged between 50 and 69” there is no guidance for men aged 70+ However, there is strong evidence that men aged over 70 with no symptoms related to prostate cancer are less likely to benefit from having a PSA test
PSA Pathway - North Central London GP Website Give patient information on PSA test and patient to decide whether to proceed with test Is the PSA according to the patient’s age? Age BAUS PSA Thresholds (ng ml) 40-49 2 7 50-59 3 9 60-69 5 0 70-79 7 2 80-84 10 85+ 20 (if borderline, repeat in 1-3 months If PSA rising - refer) Does the patient have a suspicious DRE? Counsel patient on PSA
What is a normal vs abnormal PSA test score? - Prostate Matters Urologists will take into account both your age and the size of your prostate, if known, when trying to interpret what a PSA score means Roughly speaking the following is the rule of thumb: For men in their 40s and 50s: A PSA score greater than 2 5 ng ml is considered abnormal The median PSA for this age range is 0 6 to 0 7 ng ml
Age related reference range for PSA (prostate specific antigen) if PSA > 40, there is a high chance that there is nodal or metastatic spread; if PSA > 100, there is almost certainly metastatic spread; Note that reference ranges may vary between laboratories Reference: NICE (December 2021) Suspected cancer: recognition and referral; NHS Cancer screening programmes - Prostate Cancer Risk Management