CBR3 - Wikipedia Carbonyl reductase [NADPH] 3 is an enzyme that in humans is encoded by the CBR3 gene [5][6][7] The enzyme is a member of short chain dehydrogenase reductase superfamily (SDR)
CBR3 Gene - GeneCards | CBR3 Protein | CBR3 Antibody CBR3 (Carbonyl Reductase 3) is a Protein Coding gene Diseases associated with CBR3 include Renal Cell Carcinoma, Nonpapillary and Parkinson's Disease Among its related pathways are Metapathway biotransformation Phase I and II and Nuclear receptors meta-pathway
CBR3 - Carbonyl reductase [NADPH] 3 - Homo sapiens (Human) - UniProt There are conflicting results on the ability of CBR3 to metabolize menadione Although menadione was originally reported as a good substrate of CBR3 (PubMed: 15537833), results of later studies showed that CBR3 possesses very low or no activity toward menadione (PubMed: 18493841, PubMed: 19841672)
Entry - *603608 - CARBONYL REDUCTASE 3; CBR3 - OMIM By analyzing sequences from the 21q22 2 chromosomal region, Watanabe et al (1998) identified genomic clones corresponding to CBR1 (114830) and to CBR3, a novel carbonyl reductase gene The deduced 277-amino acid CBR3 protein is 84% similar to the CBR1 protein
CBR3 protein expression summary - The Human Protein Atlas Specificity of RNA expression in 17 cancer types is categorized as either cancer enriched, group enriched, cancer enhanced, low cancer specificity and not detected The RNA data was used to cluster genes according to their expression across cell lines
Regulation of Human Carbonyl Reductase 3 (CBR3; SDR21C2) Expression by . . . Here, we show that CBR3 expression is regulated via Nrf2, a key regulator in response to oxidative stress In human cancer cell lines, CBR3 mRNA was expressed differentially, ranging from very high (A549, lung) to very low (HT-29, colon; HepG2, liver) levels
CBR3 - grokipedia. com Carbonyl reductase 3 (CBR3) is a protein-coding gene located on the long arm of human chromosome 21 at position 21q22 12, encoding an enzyme that belongs to the short-chain dehydrogenase reductase (SDR) family
Gene - CBR3 Carbonyl reductase 3 (CBR3) is a short‐chain dehydrogenase reductase that plays a key role in the metabolism of both endogenous carbonyl compounds and xenobiotics
Gene: CBR3 - kb. linkedomics. org Cis-association Associations between omics data of CBR3 * The numbers are Spearman correlation coefficients and can be clicked to show the scatter plots The color and size of the circles correlate with the coefficients
CBR3 carbonyl reductase 3 - NIH Genetic Testing Registry (GTR) - NCBI Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols The enzyme is classified as a monomeric NADPH-dependent oxidoreductase