US8575305B2 - Cell penetrating peptides - Google Patents The present invention discloses cell penetrating peptides and conjugates of a cell penetrating peptide and a cargo molecule 2009-05-15 Priority to US12 996,307 priority Critical patent US8575305B2 en 2029-05-15 Anticipated expiration legal-status Critical Links USPTO; USPTO PatentCenter; USPTO Assignment; Espacenet; Global Dossier;
Dehua Pei Inventions, Patents and Patent Applications - Justia Patents . . . The polypeptide conjugates disclosed herein comprise a polyarginine peptide and a cyclic cell-penetrating peptide (cCPP) conjugated, directly or indirectly, to the polyarginine peptide The present disclosure demonstrates that cCPPs conjugated to polyarginine peptides can be used to deliver nucleic acids to the cytosol of cells
US8614194B1 - Anionic cell penetrating peptide and its . . . - Google Patents The cell penetrating peptide includes an amino acid sequence of D n , in which D represents an aspartate residue and 2≦n≦15 Other CPPs, such as polyarginine-based peptides, are synthesized and employed as a tool for intracellular delivery of therapeutics PATENT EXPIRED FOR FAILURE TO PAY MAINTENANCE FEES (ORIGINAL EVENT CODE: EXP
CN113150075A - Novel cyclic poly-arginine membrane-penetrating peptide . . . The invention discloses a novel cyclic poly-arginine cell-penetrating peptide molecule and a synthesis method and application thereof, wherein the structural formula of the cyclic poly-arginine cell-penetrating peptide molecule is as follows: the invention firstly synthesizes the linear sequence K (Mtt) RrRrRrRrRrRrE (OAll) (PEG) of the cyclic membrane-penetrating peptide molecule by using the
Improved cell-penetrating peptides and fusion proteins - Google Patents The present invention relates to diagnostic and therapeutic molecules comprising derivatives of a cell-penetrating protein and any appropriate dominant-negative peptide and or protein WO2022129926A1 - Improved cell-penetrating peptides and fusion proteins - Google Patents 2021-12-16 Priority to US18 257,827 priority patent US20240052005A1 en
US20190127431A1 - Cell-penetrating peptide - Google Patents A cell-penetrating peptide has remarkably excellent cell penetration efficiency, and is capable of penetrating 100% into all cells within 1 hour even in an environment including serum or sera, as well as a stable structure Cell-penetrating peptide - Google Patents Cell-penetrating peptide Download PDF Info Publication number
US7943581B2 - Cell penetrating peptides for . . . - Google Patents a cell-penetrating peptide according to the invention can further comprise, covalently linked to the C-terminal extremity of the peptidic core of SEQ ID No: 1, one or several groups chosen amongst a cysteamide, a cysteine, a thiol, an amide, a carboxyl, a linear or ramified C 1 -C 6 alkyl optionally substituted, a primary or secondary amine, an osidic derivative, a lipid, a phospholipid, a
Google Patents Search within the title, abstract, claims, or full patent document: You can restrict your search to a specific field using field names Use TI= to search in the title, AB= for the abstract, CL= for the claims, or TAC= for all three For example, TI=(safety belt) Search by Cooperative Patent Classifications (CPCs): These are commonly used to represent ideas in place of keywords, and can also
US10421784B2 - Cell penetrating peptides for . . . - Google Patents A cell-penetrating peptide characterized in that it comprises an amino acid sequence: X 1 X 2 X 3 WWX 4 X 5 WAX 6 X 3 X 7 X 8 X 9 X 10 X 11 X 12 WX 13 R (SEQ ID No: 10), wherein X 1 , is beta-A or S, X 2 is L or none, X 3 is R or none, X 4 is L, R or G, X 5 is R, W or S, X 6 is S, P or T, X 7 is W or P, X8 is F, A or R, X 9 is S, L, P or R, X 10 is R or S, X 11 n is W or none, X 12 is A, R or
US20170057997A1 - Cell penetrating peptide and method . . . - Google Patents a cell-penetrating peptide of the present disclosure can effectively deliver a protein into human cells and tissues, can deliver a protein with higher efficiency in comparison with a TAT peptide that is commercially used as a cell-penetrating peptide, and can also be usefully used in delivering a biologically active substance such as a protein, a genetic material, a chemical compound, etc
US11298319B2 - Cell penetrating peptide (CPP)-mediated . . . - Google Patents The present invention relates to methods for loading extracellular vesicles (EVs) with a pharmacological agent The invention discloses the use of cell-penetrating peptides as carriers into EVs, using either a non-covalent or covalent loading approach Furthermore, the present invention pertains to medical uses and compositions comprising such pharmacological agent-loaded EVs