DNA Methylation Patterns Associated with Tinnitus in Young . . . - Springer DNA methylation patterns are tissue-specific, but the tissues involved in tinnitus are not easily accessible in humans This pilot study used saliva as a surrogate tissue to identify differentially methylated CpG regions (DMRs) associated with tinnitus
COMT and the neurogenetic architecture of hearing loss induced tinnitus As the COMT polymorphism is especially prominent in the prefrontal cortex and has been associated with auditory gating, we hypothesize that tinnitus patients with this polymorphism have altered activity in the ventromedial prefrontal anterior cingulate areas that modulates the tinnitus percept
Transsulfuration pathway - Wikipedia The production of homocysteine through transsulfuration allows the conversion of this intermediate to methionine, through a methylation reaction carried out by methionine synthase
Methylation and BloodSugar Balance - OrganiClinic Methylation is a fundamental biochemical process that transfers a methyl group (one carbon and three hydrogens—CH₃) onto DNA, proteins, neurotransmitters, and hormones Think of it as the body’s “on off” switch for gene expression, detoxification, hormone metabolism, and more
Methylation | DNAlysis Methylation, or one-carbon metabolism, is the process of producing and then donating a methyl group to a substrate
Regulators of the transsulfuration pathway - Wiley In this review, we focus on the regulation of the transsulfuration pathway pertaining to cysteine and H2S, which could be targeted to develop novel therapeutics This article is part of a themed section on Chemical Biology of Reactive Sulfur Species