Turn to the liposomal amphotericin B agent that can be kinder to the . . . Mechanism of action Amphotericin B, the active ingredient of AmBisome® (amphotericin B) liposome for injection, acts by binding to the sterol component, ergosterol, of the cell membrane of susceptible fungi It forms transmembrane channels leading to alterations in cell permeability through which monovalent ions (Na+, K+, H+, and Cl-) leak out of the cell, resulting in cell death While