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  • Metabolic cardiomyopathies - PMC
    Metabolic cardiomyopathies can be caused by disturbances in metabolism, for example diabetes mellitus, hypertrophy and heart failure or alcoholic cardiomyopathy Deficiency in enzymes of the mitochondrial β-oxidation show a varying degree of cardiac manifestation
  • Metabolic cardiomyopathy: A review and pooled analysis of . . .
    Cardiomyopathies (CM) are potentially fatal heart muscle diseases and one of the leading causes of heart failure as well as indication for heart transplantation Understanding their pathogenesis is clinically relevant to improve diagnosis, management and consequently minimize the current unacceptably high mortality rates
  • Cardiomyopathy - Symptoms and causes - Mayo Clinic
    Cardiomyopathy (kahr-dee-o-my-OP-uh-thee) is a disease of the heart muscle It causes the heart to have a harder time pumping blood to the rest of the body, which can lead to symptoms of heart failure
  • Metabolic Cardiomyopathy - SpringerLink
    Metabolic cardiomyopathies represent a large heterogeneous group of diseases caused by inborn errors of metabolism (IEM) So far, more than 1000 distinct disorders of metabolism have been described Cardiac involvement is present in about 5% of these metabolic defects
  • Metabolic changes in hypertrophic cardiomyopathies: scientific update . . .
    Herein, we provide an overview of recent insights on metabolic changes in genetic hypertrophic cardiomyopathy and discuss several therapies, which may be explored to target disturbed metabolism and prevent onset of cardiac hypertrophy
  • Metabolic Cardiomyopathy: Journal of Inherited Metabolic Disease
    Cardiomyopathy is a major symptom in over 50 different IMDs ranging from disorders involving energy metabolism such as fatty acid oxidation, mitochondrial and thiamine metabolism disorders to disorders of complex molecule accumulation such as glycogen and lysosomal storage disorders, as well as small molecule catabolism defects such as
  • Pathogenesis and Pharmacology of Metabolic Cardiomyopathy
    Metabolic cardiomyopathy (MeC) is a special type of cardiovascular disease caused by systematic metabolic disorders inherited or acquired during adulthood
  • Metabolic Cardiomyopathy, 2nd ed. - AHA ASA Journals
    discuss cardiomyopathies related to specific metabolic disorders such as carnitine deficiency, defects in long chain fatty acid oxidation, and Gaucher’s disease
  • Mitochondrial CaMKII causes adverse metabolic reprogramming . . . - Nature
    We map a metabolic pathway that rescues disease phenotypes in mtCaMKII mice, providing insights into physiological and pathological metabolic consequences of CaMKII signaling in mitochondria





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