MMR, Tdap, varicella: spacing intervals and managing vaccine records Same day or 4 weeks apart is the guiding rule for live vaccines like MMR and varicella Inactivated or toxoid vaccines (like Tdap) don’t have that same-day 28-day rule with live vaccines; they can be given together
Measles, Mumps and Rubella – Institute for Vaccine Safety Those without such evidence of immunity should be given MMR vaccine, excluding women who are pregnant or currently attempting to become pregnant (pregnancy should be avoided for at least 4 weeks following MMR vaccination)
Measles, Mumps, Rubella (MMR) Vaccination and Management of . . . - ACOG MMR vaccination should not be administered during pregnancy, and it is recommended to avoid pregnancy for 28 days after receipt of MMR However, MMR can be given in the postpartum period even while breastfeeding, ideally before hospital discharge
Vaccine Recommendations and Guidelines of the ACIP But in this situation the live vaccine rule prevents the grace period from being applied to the second dose of either vaccine, because Varicella-2, if administered earlier than 4 weeks, could potentially be affected by MMR1, and likewise MMR2 could be affected by Varicella-1
Measles, mumps, and rubella immunization in adults Issues related to the use of combination MMR vaccine in adults will be discussed here; use of MMR and measles, mumps, rubella, and varicella (MMRV) immunization in infants, children, and adolescents is discussed separately
Specifications for Measles, Mumps, and Rubella (MMR) and Varicella Vaccines MMR, Varicella, and other live-virus vaccines (live influenza FluMist®) can be given on the same day but otherwise must be separated by 28 days; if given before 28 days, the later dose is invalid The four-day grace period does not apply for the interval between two live virus vaccines