MITF Gene - GeneCards | MITF Protein | MITF Antibody MITF (Melanocyte Inducing Transcription Factor) is a Protein Coding gene Diseases associated with MITF include Tietz Albinism-Deafness Syndrome and Waardenburg Syndrome, Type 2A Among its related pathways are MITF-M-dependent gene expression and Transport of the SLBP independent Mature mRNA
MITF—the first 25 years - PMC - PubMed Central (PMC) In the 25 yr since the gene encoding the microphthalmia-associated transcription factor (MITF) was first isolated, MITF has emerged as a key coordinator of many aspects of melanocyte and melanoma biology Like all transcription factors, MITF binds to specific DNA sequences and up-regulates or down-regulates its target genes
About Mutations in the MITF Gene - Memorial Sloan Kettering Cancer Center A MITF mutation increases your risk of skin cancer and kidney cancer While a MITF mutation means you have a somewhat higher risk of developing cancer than the average person, it may not fully explain why your blood relatives have cancer
Microphthalmia-Associated Transcription Factor (MITF): Multiplicity in . . . factor (MITF) regulates the differentiation and development of melanocytes and retinal pigment epithelium and is also responsible for pigment cell-speci®c transcrip-tion of the melanogenesis enzyme genes Hetero-zygous mutations in the MITF gene cause auditory± pigmentary syndromes
Hereditary Cancer Genetic Test Results - Quest Diagnostics MITF gene have a higher-than-average chance to develop melanoma and renal cancer The chance to develop cancer is increased, but not everyone with a pathogenic or likely pathogenic variant will develop cancer Cancer risk Information about cancer risks related to pathogenic variants in MITF is still emerging and is likely to change over time