UNC0638 inhibits SARS-CoV-2 entry by blocking cathepsin L . . . - PubMed Since the outbreak of SARS-CoV-2, viral mutations have posed significant challenges in identifying therapeutic targets and developing broad-spectrum antiviral drugs Post-translational modifications of genes involved in interferon production and signaling pathways play a crucial role in regulating i …
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GitHub - microsoft SoftTeacher: Semi-Supervised Learning, Object . . . By Mengde Xu*, Zheng Zhang*, Han Hu, Jianfeng Wang, Lijuan Wang, Fangyun Wei, Xiang Bai, Zicheng Liu This repo is the official implementation of ICCV2021 paper "End-to-End Semi-Supervised Object Detection with Soft Teacher"
UNC0638 inhibits SARS-CoV-2 entry by blocking cathepsin L maturation In this study, we demonstrated that knockdown or knockout of EHMT2 inhibited SARS-CoV-2 infection, and inhibitors of EHMT2, including UNC0638, UNC0642, and BIX01294 showed similar restrictive effects Mechanistically, the EHMT2 inhibitor UNC0638 restricts spike-mediated cell entry by inhibiting the maturation of CTSL, a critical protease required for SARS-CoV-2 entry via the endosomal pathway
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On-Device Training Under 256KB Memory - NIPS Authors Ji Lin, Ligeng Zhu, Wei-Ming Chen, Wei-Chen Wang, Chuang Gan, Song Han Abstract On-device training enables the model to adapt to new data collected from the sensors by fine-tuning a pre-trained model Users can benefit from customized AI models without having to transfer the data to the cloud, protecting the privacy However, the training memory consumption is prohibitive for IoT