Clinical trials - World Health Organization (WHO) Clinical trials are a type of research that studies new tests and treatments and evaluates their effects on human health outcomes People volunteer to take part in clinical trials to test medical interventions including drugs, cells and other biological products, surgical procedures, radiological procedures, devices, behavioural treatments and
Guidance for best practices for clinical trials The Guidance for Best Practices for Clinical Trials has been developed in response to the 2022 World Health Assembly resolution (WHA75 8) on strengthening clinical trials This guidance provides Member States with a framework for integrating robust and ethical clinical trial practices into their national health systems, enhancing the quality
Groundbreaking Ebola vaccination trial launches today in Uganda IAVI, the provider of the vaccine, conducted trials for safety and immunogenicity It is also the first clinical trial of the vaccine during an outbreak The principal investigators from Makerere University and the Uganda Virus Research Institute (UVRI), with support from WHO and other partners, have worked tirelessly to get the trial ready in
Clinical trials in children - World Health Organization (WHO) Clinical trials in children are essential to develop age-specific, empirically-verified therapies and interventions to determine and improve the best medical treatment available Ethical Implications The ICTRP is committed to promoting the conduct of ethical and relevant clinical trials in children by improving access to guidelines, regulations
Trial registration - World Health Organization (WHO) The registration of all interventional trials is considered to be a scientific, ethical and moral responsibility because: There is a need to ensure that decisions about health care are informed by all of the available evidence; It is difficult to make informed decisions if publication bias and selective reporting are present
WHO releases global action plan to strengthen clinical trial ecosystems WHO has published the Global action plan for clinical trial ecosystem strengthening (GAP-CTS), a key implementation tool aligned with World Health Assembly resolution WHA75 8 (2022) on strengthening clinical trials The plan outlines nine priority actions to support countries and stakeholders reform and sustain clinical trial systems that are fit for purpose, inclusive and locally led
WHO landscape of clinical trials on monoclonal antibodies Number of trials on monoclonal antibodies (mAbs) peaked in 2021 with 342 trials regsitered (see Chart A 1) In the decade 2004-2013 1,207 trials were conducted on mAbs, while in 2014-2023 2,066 trials were conducted (filter Action (decade) and see number N) Most trials are conducted in the United States of America (see map B 1)
Clinical trials - World Health Organization (WHO) Currently, the registry displays over 34,000 clinical trials Pan African Clinical Trial Registry ; The PACTR is a regional register of clinical trials conducted in Africa An open-access platform where clinical trials can be registered free of charge, providing an electronic database of planned trials and trials currently in progress
WHO Global Clinical Trials Forum (GCTF) - World Health Organization (WHO) The Global Clinical Trials Forum (GCTF) is a World Health Organization (WHO) managed network The network aims to enable activities of partners for implementation of WHO's guidance on best practices for clinical trials, guidance developed at the request of World Health Assembly resolution WHA 75 8 A Global Action Plan for Clinical Trial