Pathology Outlines - Dysplasia Dysplasia is a biliary intraepithelial neoplasia that arises in the gallbladder; it is a precursor lesion to gallbladder carcinoma with high risk of progression
Intraductal papillary neoplasm of the bile ducts Biliary intraepithelial neoplasia (BilIN): Also is located within lumen of large intrahepatic bile ducts Typically is < 3 mm in height (not mass forming) Simple cyst, simple hepatic cyst, simple biliary cyst, bile duct cyst: Lacks papillary projections Intraductal tubulopapillary neoplasm of the bile duct (Mod Pathol 2015;28:1249):
Pathology Outlines - Liver intrahepatic bile ducts Biliary dysplasia: biliary intraepithelial neoplasia (BILIN) (pending) intraductal papillary mucinous neoplasm (IPMN) of bile ducts (pending) intraductal oncocytic neoplasm (IOPN) of bile ducts (pending) mucinous cystic neoplasm
Pathology Outlines - Adenomyomatous hyperplasia In general, biliary dysplasia (biliary intraepithelial neoplasia [BilIN]) can be either low grade or high grade and is recognized by the abrupt transition from normal mucosa with nuclear hyperchromasia, overlapping and enlargement in low grade, with the inclusion of those features as well as loss of nuclear polarity nuclear stratification seen
Pathology Outlines - Gallbladder carcinoma Cystic duct margin is free from biliary intraepithelial neoplasia (BilIN) or carcinoma One lymph node, negative for carcinoma (0 1) Lymphovascular invasion is not identified pT2a, N0, M-not applicable (AJCC 8th edition) Please see synoptic report Background gallbladder with chronic cholecystitis Cholelithiasis
WHO reporting system for pancreaticobiliary cytopathology Pancreas - Papanicolaou system: 6 tiered reporting system: nondiagnostic, negative (for malignancy), atypical, neoplastic (benign or other), suspicious (for malignancy) and positive or malignant
WHAT’S NEW IN PATHOLOGY? - PathologyOutlines. com Gallbladder Extrahepatic bile ducts • Grading of biliary intraepithelial neoplasia (BilIN) is now two tier (low and high grade) rather than three tier