Apligraf® Living Cellular Skin Substitute Learn more about Apligraf®, the living cellular skin substitute that can speed the healing of venous leg ulcers and diabetic foot ulcers
Apligraf® Overview | Apligraf® The living cells of Apligraf are bioactive and poised to heal 9,12 In an in vitro study, meshed Apligraf was incubated over a dermal lattice for up to 5 days By 24 hours, the wound was closed—demonstrating that Apligraf had healed itself 9
Product Details | Apligraf® Step 2: Applying Apligraf 2A Place Apligraf over the wound with the dermal (glossy) side directly in contact with the wound surface 2B Using a saline-moistened cotton tip applicator, smooth Apligraf onto the wound bed so there are no pockets or wrinkled edges 2A-2B
Rediscover healing that remains ahead of its time. - Apligraf Dermal layer: Contains living fibroblasts that proliferate and produce human collagen and ECM proteins as well as growth factors cytokines 2,11,12 Normal skin Apligraf * Keratinocyte stem cells are key contributors to the signaling profile
300-111-12 Apligraf PI Apligraf is supplied as a living, bi-layered skin substitute: the epidermal layer is formed by human keratinocytes and has a well-differentiated stratum cornaum: the dermal layer is composed of human fibroblasts in a bovine Tune Lealladen lattice while matrix ercbains and cytokines found in human Papel collagen amnet wanne hainx proseite cytulunes iduna innen melanocytes, macrophages