Do You Have COMT Gene Mutation, COMT Symptoms Testing Catechol-O-methyltransferase (COMT) or COMT enzyme activity is important to the areas of the pre-frontal cortex, this area of the brain is involved with personality, inhibition of behaviours, short-term memory, planning, abstract thinking, and emotion s
Catechol-O-methyltransferase - Wikipedia Catechol-O-methyltransferase (COMT; EC 2 1 1 6) is one of several enzymes that degrade catecholamines (neurotransmitters such as dopamine, epinephrine, and norepinephrine), catecholestrogens, and various drugs and substances having a catechol structure [7] In humans, catechol- O -methyltransferase protein is encoded by the COMT gene [8]
COMT gene: MedlinePlus Genetics The COMT gene provides instructions for making an enzyme called catechol-O-methyltransferase Learn about this gene and related health conditions
How the COMT Gene Impacts Mental Health Treatment - Genomind The relative lack of dopamine transporters in the PFC means that dopamine levels in the PFC are largely determined by activity of the COMT enzyme If clinically indicated, patients that display the COMT Val Val genotype may benefit from agents that increase synaptic dopamine