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    To conclude this review, we will discuss newly developed technologies that hold promise to address the limitations of current gene editors for clinical use that include the development of new delivery vehicles to direct gene editors to specific tissues, hyperaccurate CRISPR systems that decrease off-target effects, and gene editing tools that
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    The past decade has witnessed the discovery, engineering, and deployment of RNA-programmed genome editors across many applications By leveraging CRISPR-Cas9’s most fundamental activity to create a targeted genetic disruption in a gene or gene regulatory element, scientists have built successful platforms for the rapid creation of knockout mice and other animal models, genetic screening, and





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