GEMME: A Simple and Fast Global Epistatic Model Predicting Mutational . . . Our method is implemented as a fully automated tool, Global Epistatic Model for predicting Mutational Effects (GEMME), available as a downloadable package and as a webserver at www lcqb upmc fr GEMME We show that GEMME is faster than state-of-the-art methods by several orders of magnitude
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GEMME: A Simple and Fast Global Epistatic Model Predicting . . . - PubMed Here, we present Global Epistatic Model for predicting Mutational Effects (GEMME) (www lcqb upmc fr GEMME), an original and fast method that predicts mutational outcomes by explicitly modeling the evolutionary history of natural sequences
GEMME: a simple and fast global epistatic model predicting . . . - bioRxiv 166 GEMME’s predictive model globally accounts for epistasis by explicitly looking at the whole 167 sequence context when assessing the effect of a particular mutation It is applicable to single site 168 mutations and also to combinations of mutations (see Methods)
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