Infantile Neuroaxonal Dystrophy (INAD): Symptoms Prognosis Children with infantile neuroaxonal dystrophy (INAD) inherit a gene mutation that causes lipids to build up on nerves This rare lipid storage disorder affects your child’s vision, motor skills and development
Understanding INAD – INADCure Foundation Infantile Neuroaxonal Dystrophy is an ultra-rare disorder Its specific incidence is unknown, however it is estimated that INAD affects approximately 150 children worldwide A diagnosis of INAD can now be confirmed through genetic testing of the PLA2G6 gene
INAD | NBIA - NBIAcure The symptoms of INAD (infantile neuroaxonal dystrophy) usually start to appear between the ages of 6 months and 1 year A common pattern in young children is loss of skills and progression of the disorder over time
Orphanet: Infantile neuroaxonal dystrophy Infantile neuroaxonal dystrophy atypical neuroaxonal dystrophy (INAD atypical NAD) is a type of neurodegeneration with brain iron accumulation (NBIA) characterized by psychomotor delay and regression, increasing neurological involvement with symmetrical pyramidal tract signs and spastic tetraplegia
Infantile neuroaxonal dystrophy: MedlinePlus Genetics Infantile neuroaxonal dystrophy is a disorder that primarily affects the nervous system Individuals with infantile neuroaxonal dystrophy typically do not have any symptoms at birth, but between the ages of about 6 and 18 months they begin to experience delays in acquiring new motor and intellectual skills, such as crawling or beginning to speak
Infantile Neuroaxonal Dystrophy - BrainFacts Infantile neuroaxonal dystrophy (INAD) is a rare inherited neurological disorder It affects axons, the part of a nerve cell that carries messages from the brain to other parts of the body, and causes progressive loss of vision, muscular control, and mental skills