安裝中文字典英文字典辭典工具!
安裝中文字典英文字典辭典工具!
|
- Mechanisms of protein toxicity in neurodegenerative diseases
Protein toxicity is a unifying feature of both sporadic and familial cases of neurodegenerative diseases One of the mechanisms by which protein toxicity occurs is through genetic mutations
- How do toxic proteins accumulate in Alzheimer’s and other diseases?
Under normal circumstances, tau protein is part of the brain’s infrastructure, important for stabilizing neurons into their proper shapes But sometimes tau gets knotted up into tangles and turns toxic, injuring brain tissue and causing tauopathies, a group of brain diseases characterized by problems with learning, memory and movement
- Toxic Protein and Aging Combine Forces to Drive Brain Disease
New IRP research suggests that the aged brain is a fertile ground for the spread of a harmful protein associated with several neurological diseases, and that the toxic protein itself ages immune cells in the brain 1
- How to clear the toxic tau protein that can lead to Alzheimer’s and . . .
USC Stem Cell scientists discover a new way to rid cells of toxic tau protein in a study involving mice and lab-grown human “mini-brains,” known as organoids
- A Backlog of Brain Crud: Cleaning Out the Bad Proteins in Dementia
In each disease, one or more protein loses its natural structure and self-assembles into large conglomerates These are toxic Worse, they are difficult for the brain to remove In Alzheimer’s disease, the abnormal proteins are called beta-amyloid and tau
- Brain Protein Overload: Causes, Effects, and Treatments
Explore the causes, effects, and treatment options for brain protein overload, including neurological disorders, genetic factors, and emerging therapies
- Alzheimers: Why do toxic protein clumps form, and how to fight them?
New research in worm models suggests that natural aging processes, as well as toxic beta-amyloid may drive the accumulation of harmful protein clumps associated with Alzheimer's disease
|
|
|