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  • The clinical relevance of oliguria in the critically ill patient . . .
    Background Urine output is widely used as one of the criteria for the diagnosis and staging of acute renal failure, but few studies have specifically assessed the role of oliguria as a marker of acute renal failure or outcomes in general intensive care unit (ICU) patients Using a large multinational database, we therefore evaluated the occurrence of oliguria (defined as a urine output < 0 5
  • Comparison of methods to normalize urine output in critically ill . . .
    Background Oliguria diagnosis includes the normalization of urine output (UO) by body weight However, the rational and the method to apply to normalize UO to body weight are unclear We aimed to explore the impact of the method applied to normalize UO on oliguria incidence and association with outcomes Methods We included all adult patients admitted to a Swiss (derivation cohort) and a US
  • Magnesium Sulfate for Pre-eclampsia and Eclampsia Management - Page 2
    Oliguria is an element of the disease process [reduced clearance by the kidneys], and not an adverse effect of magnesium sulfate use
  • Non-interventional follow-up versus fluid bolus in RESPONSE to oliguria . . .
    Background Fluid bolus therapy is a common intervention to improve urine output Data concerning the effect of a fluid bolus on oliguria originate mainly from observational studies and remain controversial regarding the actual benefit of such therapy We compared the effect of a follow-up approach without fluid bolus to a 500 mL fluid bolus on urine output in hemodynamically stable critically
  • Identification of an optimal threshold to define oliguria in critically . . .
    Background The relevance of current consensus threshold to define oliguria has been challenged by small observational studies We aimed to determine the optimal threshold to define oliguria in critically-ill patients Methods Cohort study including adult patients admitted within a multi-disciplinary intensive care unit between January 1st 2010 and June 15th 2020 Patients on chronic dialysis
  • Oliguria as predictive biomarker of acute kidney injury in critically . . .
    Introduction During critical illness, oliguria is often used as a biomarker of acute kidney injury (AKI) However, its relationship with the subsequent development of AKI has not been prospectively evaluated Methods We documented urine output and daily serum creatinine concentration in patients admitted for more than 24 hours in seven intensive care units (ICUs) from six countries over a
  • Structural, physiological or clinical outcomes to define urine output . . .
    From a physiological perspective, the traditional definition of oliguria (< 400 mL 24 h) is based on the assumption that a healthy adult excretes 600–800 mOsm of metabolic waste daily At maximal urine concentration (1200 mOsm L), at least 400 mL of urine is required for adequate waste excretion [3] However, critically ill patients likely produce less metabolic waste and rarely achieve
  • Acute kidney injury 2016: diagnosis and diagnostic workup
    Acute kidney injury (AKI) is common and is associated with serious short- and long-term complications Early diagnosis and identification of the underlying aetiology are essential to guide management In this review, we outline the current definition of AKI and the potential pitfalls, and summarise the existing and future tools to investigate AKI in critically ill patients


















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