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- Ambroxol - ALZFORUM
Ambroxol is a mucolytic compound and the main ingredient of over-the-counter cough medicines sold in many countries Syrup, tablet, and other forms are used at doses of 30 to 120 mg per day to reduce or thin mucous secretions and ease sore throat pain
- Ambroxol for the Treatment of Patients With Parkinson Disease With and . . .
Ambroxol for the Treatment of Patients With Parkinson Disease With and Without Glucocerebrosidase Gene Mutations: A Nonrandomized, Noncontrolled Trial JAMA Neurol 2020 Apr 1;77(4):427-434 PubMed Recommends Please login to recommend the paper Comments No Available Comments Make a Comment To make a comment you must login or register
- Early initiation of ambroxol treatment diminishes neurological . . .
Early initiation of ambroxol treatment diminishes neurological manifestations of type 3 Gaucher disease: A long-term outcome of two siblings Eur J Paediatr Neurol 2021 May;32:66-72 Epub 2021 Mar 31 PubMed Recommends Please login to recommend the paper Comments No Available Comments Make a Comment To make a comment you must login or
- TDP-43 (Q331K) - ALZFORUM
This transgenic mouse model of ALS overexpresses human TDP-43 with the Q331K mutation (Arnold et al , 2013) Expression of the mutant protein is driven in the brain and spinal cord by the mouse prion protein (Prp) promoter Although this model does not recapitulate cytoplasmic mislocalization of TDP
- Large Phase 2 Trial Starting Up in Genetic Parkinson’s Population
Researchers in Canada recently evaluated the ability of the chaperone ambroxol to stimulate GBA activity in a small Phase 2 Parkinson’s study, and a similar trial of ambroxol is starting up in London
- Therapeutics Search | ALZFORUM
Find a Therapeutic By Name Go NSC001 AAB-003 AADvac1 AAV-GAD AAV2-BDNF ABBV-552 ABBV-916 ABT 418 ABT-089 ABT-288 ABT-384 ABT-957 ABvac40 ACD856 Acetyl-l-carnitine HCI ACI-24 060 ACI-3024 ACI-7104 056 Acitretin ACP-204 ADEL-Y01 Aduhelm AF 102B Affitope AD02 AGB101 AIT-101 AKST4290 AL002 AL003 AL044 AL101 ALIA-1758 Allopregnanolone Alpha
- Therapeutics | ALZFORUM
Find a Therapeutic By Name Go NSC001 AAB-003 AADvac1 AAV-GAD AAV2-BDNF ABBV-552 ABBV-916 ABT 418 ABT-089 ABT-288 ABT-384 ABT-957 ABvac40 ACD856 Acetyl-l-carnitine HCI ACI-24 060 ACI-3024 ACI-7104 056 Acitretin ACP-204 ADEL-Y01 Aduhelm AF 102B Affitope AD02 AGB101 AIT-101 AKST4290 AL002 AL003 AL044 AL101 ALIA-1758 Allopregnanolone Alpha
- ALZFORUM | NETWORKING FOR A CURE
Mazzulli JR, Xu YH, Sun Y, Knight AL, McLean PJ, Caldwell GA, Sidransky E, Grabowski GA, Krainc D Gaucher disease glucocerebrosidase and α-synuclein form a bidirectional pathogenic loop in synucleinopathies
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