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- NeurobiologyofDisease ImpairmentofGlymphaticPathwayFunctionPromotesTau . . .
16180 • TheJournalofNeuroscience,December3,2014 • 34(49):16180–16193 transport, we termed this paravascular pathway the “glymphatic system ”Inthepresentstudy,weevaluatewhetherthedisruption of perivascular AQP4 localization following TBI (Lu et al ,
- Impairment of Glymphatic Pathway Function Promotes Tau Pathology after . . .
Traumatic brain injury (TBI) is an established risk factor for the early development of dementia, including Alzheimer's disease, and the post-traumatic brain frequently exhibits neurofibrillary tangles comprised of aggregates of the protein tau We have recently defined a brain-wide network of paravascular channels, termed the “glymphatic” pathway, along which CSF moves into and through
- Journal of Neuroscience
To capture the 3D nature of cultured neurons as well as their abundant connections to neighboring neurons, Chunta Ho and colleagues applied custom processing (shadows, gaussian blur, and lookup tables) to an image of a neuron fluorescently labeled via adeno
- Systems Circuits GlialDysfunctionintheMouseHabenulaCausesDepressive . . .
firing, burst oscillations of action potentials, and silence in vitro (Wilcoxetal ,1988;KimandChang,2005) Thesefiringpatterns, which are outputs from the LHb, are under the influence of the excitatory and inhibitory inputs from structures, such as the en-topeduncular
- Systems Circuits ExcitationandInhibitionCompetetoControlSpikingduring . . .
1998) Toexaminethenatureofspikegenerationandtheroleof inhibition in controlling spiking during ripples, we recorded the membrane potential of CA1 pyramidal cells
- NeurobiologyofDisease -SynucleinIsLocalizedtoMitochondria-AssociatedER . . .
SNCA • •
- Behavioral Cognitive WhentheBrainTakesaBreak:AModel-BasedAnalysisof . . .
16286 • TheJournalofNeuroscience,December3,2014 • 34(49):16286–16295 nition (Fig 1), we can identify and measure a goal-monitoring and a response-inhibition component of executive control and
- Systems Circuits DistributedandDynamicNeuralEncodingofMultiple . . .
16180 • TheJournalofNeuroscience,December9,2015 • 35(49):16180–16198 tent of “separation” between two transparently moving stimuli can be conveniently controlled by manipulating the angular dif-
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