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- Enzalutamide: targeting the androgen signalling pathway in . . . - PubMed
Enzalutamide, the first approved AR signalling inhibitor, has a novel mode of action targeting AR signalling at three key stages The direct mode of action of enzalutamide has been shown to translate into clinical responses in patients with mCRPC
- Enzalutamide: targeting the androgen signalling pathway in metastatic . . .
Enzalutamide, the first approved AR signalling inhibitor, has a novel mode of action targeting AR signalling at three key stages The direct mode of action of enzalutamide has been shown to translate into clinical responses in patients with mCRPC
- Clinical Efficacy of Enzalutamide vs Bicalutamide Combined With . . .
Enzalutamide is a second-generation androgen receptor inhibitor that shows enhanced cytotoxic effects in prostate cancer cells by blocking nuclear translocation and DNA binding 1 Compared with bicalutamide, enzalutamide has demonstrated superior progression-free survival in metastatic castrate-resistant prostate cancer (mCRPC) 2 This study
- Enzalutamide in Prostate Cancer, A Review on Enzalutamide and cancer
Enzalutamide induces apoptosis of prostate cancer cells Enzalutamide is effective in metastatic castration-resistant prostate cancer in patients with progression after docetaxel treatment and in chemotherapy-naive patients
- Deep and ongoing response of castrate-resistant prostate cancer on very . . .
Enzalutamide is an orally administered drug that blocks signaling in the androgen receptor with clinical activity in both chemotherapy–naive and post-chemotherapy patients with castrate-resistant prostate cancer (CRPC) [1, 2]
- Improved Outcomes with Enzalutamide in Biochemically Recurrent Prostate . . .
Evidence from prospective, phase 3 clinical trials has shown that treatment intensification with next-generation hormonal therapies, such as enzalutamide, prolongs imaging-based progression-free
- Enzalutamide: targeting the androgen signalling pathway in metastatic . . .
Enzalutamide, the first approved AR signalling inhibitor, has a novel mode of action targeting AR signalling at three key stages The direct mode of action of enzalutamide has been shown to translate into clinical responses in patients with mCRPC
- Enzalutamide: targeting the androgen signalling pathway in . . . - Wiley
Enzalutamide, the first approved AR signalling inhibitor, has a novel mode of action targeting AR signalling at three key stages The direct mode of action of enzalutamide has been shown to translate into clinical responses in patients with mCRPC
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