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- rs1800795 - SNPedia
A study of 238 Caucasians with type-2 diabetes concluded that rs1800795(C) carriers have an insulin resistance "IL-6-sensitive" phenotype and perhaps strategies to manage insulin resistance should be different between (C) carriers vs (G;G) patients
- Association of IL-6 G-174C (rs1800795) variant with the susceptibility . . .
Whole blood samples from 126 Egyptian patients with HCC (111 with HCV and 15 with HBV), as well as 126 age- and sex-matched healthy individuals, were used to extract DNA Using PCR-based allele-specific amplification (ASA), the existence of the IL-6 G-174C polymorphism was investigated
- Association of IL-6 174G C (rs1800795) and 572C G (rs1800796 . . .
Several studies have been performed to investigate association between IL-6 174G C (rs1800795) and 572C G (rs1800796) gene polymorphisms and osteoporosis predisposition However, the results were conflicting
- Impact of IL-6 rs1800795 and rs1800796 polymorphisms on . . . - Springer
The IL6 promoter polymorphisms rs1800795 G > C (-174G C) and rs1800796 G > C (572 G > C), which affect IL-6 expression levels, have been extensively studied Notably, the rs1800795 G > C variant may be associated with significant clinical consequences in the lungs, including elevated IL-6 expression levels (Bouhniz et al 2020 ) and a decrease
- IL-6 gene rs1800795 polymorphism and diabetes . . . - Research Square
Background Over the past two decades, many studies concentrated the association between a common polymorphism ( rs1800795 ) from interleukin-6 (IL-6) gene and Diabetes Mellitus (DM) risk have been published, however, the results remain ambiguous and indefinite Methods In current, we performed
- Polymorphisms rs1800795 of interleukin-6 and rs2228145 of interleukin-6 . . .
We investigated the IL-6 promoter -174G>C (rs1800795) and IL-6R Asp358Ala (rs2228145) polymorphisms in 141 Euro-Brazilian patients with adult-onset type 1 diabetes (diagnosis > 18 years old) and 150 healthy controls, matched by gender and age Genotyping for both polymorphisms was performed by PCR-RFLP
- PKP-023 Interleukin 6 G gt;G genetic polymorphism (RS1800795) and the . . .
Previous studies have shown that G allele at the -174G >C (rs1800795) polymorphism is related to high producing IL-6 Purpose The aim of our study was to explore the potential role of IL-6 genetic polymorphisms as a predictor of tocilizumab efficacy in RA patients and to compare the results with a previous GWAS
- IL6-174G C (rs1800795) Polymorphism Rather than IL6R (rs2228145 and . . .
Our preliminary study revealed significant association of IL6 −174G C (rs1800795) with susceptibility to Juvenile Idiopatic Arthritis (JIA) in children and a higher frequency of the -174C allele in adult patients with RA, reaching statistical significance in case of RF-negative RA subtype
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