New Study Confirms that Cancer Cells Ferment Glutamine December 2024 marked the culmination of this study when the paper was published in ASN Neuro more Over the last seven years, The Seyfried Lab at Boston College designed and carried out
Controlling cancer cells gluttony for glutamine - ScienceDaily Researchers describe two enzymes newly identified for their roles in regulating macropinocytosis, a process cancer cells use to snatch extra nutrients from the jelly-like substance between
Glutamine: The Surprising Link to Prostate Cancer -thoughts? While Warburg identified cancer as a mitochondrial metabolic disease, this study clarifies that tumors utilize two fermentable fuels—glucose and glutamine—for survival and growth The study challenges the traditional view that oxygen consumption in tumors is linked to ATP production through oxidative phosphorylation
Filament formation enables cancer cells’ glutamine addiction In a study published in the journal Nature Communications, scientists detail how multi-enzyme structures, called filaments, are instrumental in fueling cancer activity Blocking the formation of these filaments may offer new ways to control cancer cell proliferation
Glutamine’s double-edged sword: fueling tumor growth and offering . . . A recent study demonstrated that Lobetyolin disrupts Gln metabolism by downregulating SLC1A5 expression in MDA-MB-231 and MDA-MB-468 breast cancer cells, induces apoptosis in these cells and exerts anti-tumor effects
Filament formation enables cancer cells’ glutamine addiction Blocking the formation of filaments – multi-enzyme structures that fuel cancer activity – may offer new ways to control cancer cell proliferation, according to a new study led by Cornell researchers
Controlling cancer cells’ gluttony for glutamine The scientists found that aPKC zeta and iota — and three other proteins the kinases normally interact and bind with to regulate cell polarity — are repurposed by PDAC cells lacking access to glutamine to increase macropinocytosis and scavenge more alternative resources from their surrounding environment