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- When is a troponin elevation an acute myocardial infarction?
Troponin elevations tend to be mild, with more indolent (or even flat) troponin trajectories Pericarditis and myocarditis: Due to direct injury from myocardial inflammation Cardiopulmonary resuscitation (CPR): Due to physical injury to the heart from mechanical chest compressions and from electrical shocks of external defibrillation
- Troponin elevation in conditions other than acute coronary syndromes
Acute massive or submassive pulmonary embolism is associated with elevated serum cTn levels 41 Rates of troponin positivity have been reported as 16%–47% in several studies, and troponin has been proposed as a risk determinant that may help in the decision of performing thrombolysis or embolectomy 42 – 44
- How to Interpret Elevated Cardiac Troponin Levels | Circulation
These levels used to be considered indicative of myocardial necrosis However, with high-sensitivity troponin assays, circulating cTnT or cTnI can be found in the plasma as a result of transient ischemic or inflammatory myocardial injury
- The ongoing troponin conundrum: Understanding an elevated troponin
Defining and interpreting an elevated troponin Two overarching groups of elevated cTn in the absence of MI include causes related to 1) biological factors, including other disease states that can cause acute or chronic myocardial injury, and 2) assay factors, including interferences and pre-analytical influences
- Causes of Non ACS Related Troponin Elevations
Troponin elevation in CKD is worth discussion, as the interpretation of elevation of cTn in non-ACS patients may be difficult Elevated cTn in asymptomatic CKD is common, the frequency which is dependent on the assay (cTnT > cTnI) and cut-off value used
- Troponin Test: What it Is and Normal Range - Cleveland Clinic
Troponin levels usually increase sharply within three to 12 hours after a heart attack and peak about 24 hours after the heart attack They will also remain high for several days Why would I need this test? The most common use of troponin tests is to confirm or rule out a heart attack
- Troponin elevation in non-cardiac critical illness - EMCrit Project
Baseline EKG is advisable in almost all critically ill patients This will help interpret any changes in rhythm or morphology which may occur during the patient's ICU course It may also help if the patient presents to the hospital in the future with cardiac symptoms Baseline point-of-care echocardiography may be helpful as well
- Troponin elevation pattern and subsequent cardiac and non-cardiac . . .
It outlines three main patterns of troponin elevation—acute MI, acute myocardial injury and chronic myocardial injury [2]
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