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- Hyperuricemia and Progression of Chronic Kidney Disease: A Review from . . .
Several mechanisms have been identified that explain the relationship between hyperuricemia and chronic kidney disease, including the crystal effect, renin–angiotensin–aldosterone system activation, nitric oxide synthesis inhibition, and intracellular oxidative stress stimulation, and urate-lowering therapy (ULT) has been proven to reduce
- Associations Between Hyperuricemia and Chronic Kidney Disease . . . - PubMed
For recurring bouts of hyperuricemia or gout, patients should have a blood test and joint fluid test to determine whether the medication taken is effective Interventional studies are a useful clinical research tool in clarifying the role of hyperuricemia in CKD
- Impact of hyperuricemia on chronic kidney disease and . . . - Nature
Hyperuricemia is known to be a cause of gout and has been reported to be associated with hypertension and chronic kidney diseases (CKDs) and potentially with cardiovascular diseases (CVDs) The
- Uric Acid and Chronic Kidney Disease: Still More to Do
Gout and hyperuricemia are present in 25% and 60% of patients with chronic kidney disease (CKD), respectively Despite the common association, the role of uric acid in the progression of kidney disease and in metabolic complications remains contested
- Gout and Hyperuricemia: A Narrative Review of Their . . . - MDPI
Today, gout and hyperuricemia are recognized as systemic metabolic disorders associated with a range of comorbidities, including cardiovascular diseases, chronic kidney disease, metabolic syndrome, and hepatic steatosis
- Risk of chronic kidney disease in patients with gout and the impact of . . .
An association between gout and renal disease is well-recognised but few studies have examined whether gout is a risk factor for subsequent chronic kidney disease (CKD) Additionally, the impact of urate-lowering therapy (ULT) on development of CKD
- Gout is associated with a higher risk of chronic renal disease in older . . .
Hyperuricemia and gout have been linked to chronic kidney disease (CKD) Whether the increased risk of CKD in gout is due to shared risk factors such as hypertension, diabetes or heart disease, or due to gout itself is not known
- The Shared Genetic Basis of Hyperuricemia, Gout, and Kidney Function
The genome-wide association studies have generated a range of experimentally testable hypotheses that should provide insights into the shared pathogenesis of hyperuricemia gout and chronic kidney disease
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