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- Aptamer - Wikipedia
A typical aptamer is a synthetically generated ligand exploiting the combinatorial diversity of DNA, RNA, XNA, or peptide to achieve strong, specific binding for a particular target molecule or family of target molecules
- What is an Aptamer? – Aptamers and SELEX - Base Pair Biotechnologies
Aptamers are short, single-stranded DNA or RNA (ssDNA or ssRNA) molecules that can selectively bind to a specific target, including proteins, peptides, carbohydrates, small molecules, toxins, and even live cells Aptamers assume a variety of shapes due to their tendency to form helices and single-stranded loops
- Aptamers: A Review of Their Chemical Properties and Modifications for . . .
Aptamers are short, single-stranded oligonucleotides that bind to specific target molecules The shape-forming feature of single-stranded oligonucleotides provides high affinity and excellent specificity toward targets Hence, aptamers can be used as analogs of antibodies
- Aptamers as targeted therapeutics: current potential and . . . - Nature
Nucleic acid aptamers, often termed chemical antibodies, are short, single-stranded DNA or RNA molecules (20–100 nucleotides in length) with defined structures that can specifically bind to a
- Aptamer - an overview | ScienceDirect Topics
An aptamer is a single-stranded DNA or RNA structure that folds into a unique tertiary structure for interacting with specific targets, both aptamers and targets have complementary shapes, allowing them to bind
- What Is An Aptamer?
Aptamers are synthetic affinity molecules that can specifically bind to both large and small molecules The ability of aptamers to act as antibody mimetics means that aptamers can be substituted for antibodies in a wide variety of applications, such as therapeutic targeting, biosensors, and affinity chromatography
- Aptamers - the advantages, applications and more - Blog - Lubio
Aptamers are short single-stranded DNA or RNA molecules that can bind with high affinity and specificity to their cognate targets They achieve this by folding into complex three-dimensional (3D) structures like loops and stems to attain similar binding properties to antibodies
- Aptamers - SpringerLink
Aptamers are small oligonucleotides with structural motifs that bind with high affinity and specificity to their target In the last decades, aptamer has emerged as a new opportunity in the biotherapeutic field This section summarizes the most important characteristics of aptamers and their applications in the biopharmaceutical field
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