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- Azole - Wikipedia
Azoles are a class of five-membered heterocyclic compounds containing a nitrogen atom and at least one other non-carbon atom (i e nitrogen, sulfur, or oxygen) as part of the ring [1] Their names originate from the Hantzsch–Widman nomenclature
- List of Azole antifungals - Drugs. com
Azole antifungal agents can be used to treat fungal infections of the body and skin, including athlete's foot, onychomycosis (fungal nail infections), ringworm, and vaginal candidiasis
- New Antifungal Agents with Azole Moieties - PMC
Azole compounds have been used for decades to treat fungal infections and are one of the most utilized classes of antifungal agents However, researchers have been studying new strategies and techniques to obtain new antifungal drugs with improved safety and tolerability profiles, diminished drug–drug interactions, toxicity, and resistance
- Antifungal and Antiviral Agents - EMCrit Project
Azole antifungals are generally well tolerated but are involved in numerous drug-drug interactions Look carefully for interactions before initiating these For critically ill patients with a high likelihood of fungal infection, consider empiric initiation of therapy prior to definitive diagnosis
- Azole Use in Medicine and Agriculture | Aspergillosis | CDC
Azole antifungal medications usually kill A fumigatus and treat infections, but antifungal resistance can develop after long-term use Azole fungicides work similarly to kill A fumigatus that threatens plants but can also cause A fumigatus to become resistant
- Pharmacology of azoles - UpToDate
The azoles that are available for systemic use can be classified into two groups: the triazoles (fluconazole, itraconazole, voriconazole, posaconazole, and isavuconazole) and the imidazoles (ketoconazole) An overview of the use of azole agents for the treatment of various systemic fungal infections will be reviewed here
- Azole Antifungals: Mechanisms, Types, and Resistance
Azole antifungals are key in treating fungal infections, important in both clinical and agricultural settings They treat a range of pathogenic fungi affecting humans and animals However, rising resistance highlights the need to understand azoles for effective strategies against fungal pathogens
- Antifungal Ergosterol Synthesis Inhibitors - StatPearls - NCBI Bookshelf
The primary mechanism of action involves the inhibition of ergosterol biosynthesis, leading to the disruption of fungal cell membrane integrity Exploring these azole antifungal agents involves covering indications, contraindications, drug interactions, and adverse event profiles
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