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- BRCA Gene Changes: Cancer Risk and Genetic Testing
Do inherited BRCA changes affect cancer treatment? What are BRCA1 and BRCA2 ? BRCA1 (BReast CAncer gene 1) and BRCA2 (BReast CAncer gene 2) are genes that produce proteins that help repair damaged DNA
- BRCA1 and BRCA2 (PDQ®) - NCI - National Cancer Institute
In carriers of BRCA pathogenic variants whose first cancer has an excellent prognosis, estimating the risk of a second, unrelated breast cancer is important for informing their decision to undergo risk-reducing surgery and has been described in this setting to improve survival
- Hoja informativa sobre los cambios en el gen BRCA y las pruebas genéticas
¿Influyen los cambios hereditarios en BRCA en el tratamiento del cáncer? ¿Qué son el BRCA1 y el BRCA2 ? El BRCA1 (cáncer de mama 1) y el BRCA2 (cáncer de mama 2) son genes que producen proteínas que reparan daños en el ácido desoxirribonucleico (ADN)
- MRI, Surgery Reduce Cancer Deaths in Women with BRCA Changes
For women with inherited harmful changes in BRCA genes, MRI surveillance and salpingo-oophorectomy can modestly reduce their risk of dying from breast and ovarian cancer, results from two studies show
- Cancer Risk for Women Carrying BRCA Mutations - NCI
An international team of researchers has published results from the first large prospective study of breast and ovarian cancer risk in women who carry inherited BRCA mutations The BRCA1 and BRCA2 genes code for proteins that are critical for cells to repair damaged DNA
- Discovery – BRCA Connection to Breast and Ovarian Cancer
As a result of NCI's investment, people with a family history of breast and ovarian cancer can use their BRCA test results to help make informed decisions about screening and potential risk-reducing treatment
- Riesgo de cáncer para mujeres portadoras de mutaciones en BRCA
Un equipo internacional de investigadores ha publicado los resultados del primer estudio prospectivo grande del riesgo de cáncer de seno y de ovario en mujeres portadoras de mutaciones en BRCA heredadas
- Researchers categorize thousands of BRCA2 mutations as cancerous or . . .
A team of researchers led by Shyam K Sharan, Ph D , Senior Investigator in the Mouse Cancer Genetics Program, has categorized over 6,500 possible single nucleotide variants (SNVs) in the BRCA2 protein as either benign or potentially cancerous The study was published in Nature on February 13, 2025 BRCA2 is a protein that is involved in repairing DNA and maintaining the integrity of the
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