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- CCL3 - Wikipedia
CCL3 is a cytokine belonging to the CC chemokine family that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes [6] through binding to the receptors CCR1, CCR4 and CCR5
- CCL3 Gene - GeneCards | CCL3 Protein | CCL3 Antibody
CCL3 (C-C Motif Chemokine Ligand 3) is a Protein Coding gene Diseases associated with CCL3 include Human Immunodeficiency Virus Type 1 and Aseptic Meningitis Among its related pathways are MIF Mediated Glucocorticoid Regulation and TGF-Beta Pathway
- 什么是趋化因子C-C基元配体3? - 知乎
ccl3又叫巨噬细胞炎性蛋白1-α(mip-1α),是一种由巨噬细胞分泌的趋化因子。 ccl3具有多种生物功能,如招募炎症细胞、伤口愈合、抑制干细胞和维持效应免疫反应。它能激活骨吸收细胞,直接诱导骨破坏。在炎症和骨吸收部位,分泌mip-1α ccl3的细胞会增加。
- 趋化因子 CCL3 (MIP-1 alpha CCL3) | 重组蛋白 | MCE
ccl3蛋白是具有炎症和趋化特性的单一因子,可吸引单核细胞、中性粒细胞、嗜酸性粒细胞、嗜碱性粒细胞和淋巴细胞等免疫细胞。 它对于肺部 TNF-α 的产生、中性粒细胞募集和肺损伤至关重要,并且可能作为巨噬细胞产生 TNF-α 的自分泌介质。
- CCL3基因在细胞中的表达调控机制 - 八方基因
CCL3,也被称为G0S19-1、LD78ALPHA、MIP-1-alpha、LD78和SCI,是一个位于17号染色体q12区域的基因,属于Chemokine ligands家族。 这个基因编码一种蛋白质,参与细胞间的信号传导,特别是在免疫反应中发挥重要作用。
- Macrophage Inflammatory Protein-1 Alpha (MIP-1 alpha) CCL3: As a . . .
MIP-1α CCL3 is a key chemokine that plays an important role in recruiting inflammatory cells (macrophages, lymphocytes, eosinophil, and basophils) to the site of injury or inflammation MIP-1α CCL3 is expressed by several cells upon stimulation of endotoxins such as LPS, viral proteins, and pro-inflammatory cytokines
- CCL3:调控神经再生的关键趋化因子 —— 为神经修复与疾病治疗带来新曙光 - 生物通
ccl3 是施万细胞趋化剂:实验表明,低浓度的 ccl3 即可增加大鼠和人类 sc 的迁移,且 ccl3 主要影响细胞迁移的方向,而非速度。同时,研究还发现 ccl3 通过 ccr1 和 ccr5 受体发挥作用,是缺氧巨噬细胞分泌的唯一 sc 趋化剂。
- CCL3 Signaling in the Tumor Microenvironment - PubMed
Within the tumor microenvironment, chemokines play a key role in immune cell trafficking regulation and immune landscape formulation CCL3 or macrophage inflammatory protein-1α (MIP-1α), an important chemokine implicated in both immune surveillance and tolerance, has emerged as a prognostic biomarke …
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