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- CCL3 - Wikipedia
CCL3 is a cytokine belonging to the CC chemokine family that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes [6] through binding to the receptors CCR1, CCR4 and CCR5
- CCL3 Gene - GeneCards | CCL3 Protein | CCL3 Antibody
CCL3 (C-C Motif Chemokine Ligand 3) is a Protein Coding gene Diseases associated with CCL3 include Human Immunodeficiency Virus Type 1 and Aseptic Meningitis Among its related pathways are MIF Mediated Glucocorticoid Regulation and TGF-Beta Pathway
- CCL3 Signaling in the Tumor Microenvironment - PubMed
CCL3 or macrophage inflammatory protein-1α (MIP-1α), an important chemokine implicated in both immune surveillance and tolerance, has emerged as a prognostic biomarker in both solid and hematological malignancies
- CCL3 C-C motif chemokine ligand 3 [ (human)] - National Center for . . .
CCL3 promotes VEGF-A expression and angiogenesis in human osteosarcoma cells by down-regulating miR-374b expression via JNK, ERK, and p38 signaling pathways The residues on the N-loop and beta-sheets of MIP-1a are close to both CCR1 and CCR5, and those in the C-terminal helix region are close to CCR5
- The Chemokine CCL3 Regulates Myeloid Differentiation and . . . - Nature
In murine models of chronic myelogenous leukemia (CML), CCL3 is critical for the maintenance of a leukemia stem cell population, and leukemia progression With CCL3 implicated as a potentially
- CCL3 - SpringerLink
CCL3 was initially described in 1988, as a partially purified 8-kDa protein doublet from conditioned medium of endotoxin-stimulated mouse macrophages In the view of its prominent proinflammatory chemotactic role, characterized both in vivo and in vitro at that time, this protein was denominated “macrophage inflammatory protein-1 alpha
- CCL3 Gene: Function, Role in Disease, and Clinical Applications
CCL3 is a major HIV-suppressive factor produced by CD8+ T-cells Recombinant CCL3 (MIP-1-alpha) inhibits the replication of various HIV strains, including HIV-1, HIV-2, and simian immunodeficiency virus (SIV) in a dose-dependent manner
- CCL3 | definition of CCL3 by Medical dictionary
ccl3 A gene on chromosome 17q12 that encodes a small inducible cytokine, commonly known as macrophage inflammatory protein 1 (MIP-1) alpha, which is produced by CD8+ T cells and is a major HIV-suppressive factor
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