安裝中文字典英文字典辭典工具!
安裝中文字典英文字典辭典工具!
|
- Emerging mechanistic understanding of cilia function in . . .
Cilia are microtubule-based cell projections that provide a unique environment with precise protein, lipid and second messenger concentrations, thereby creating specialized signalling hubs This
- Structure of the ciliary tip central pair reveals the unique . . .
Labeling cilia with anti-monoglycylated antibodies which preferentially labels the ciliary tip and assembling cilia in cells expressing GFP-tagged proteins allowed us to assess whether the identified tip proteins were present in short, growing cilia in dividing cells (Figure 2) In growing cilia, only SPEF1A was seen at the tip
- Lipid Modifications in Cilia Biology - PMC
Lipid modifications may help proteins travel to the cilia by two (possibly overlapping) mechanisms: (a) Facilitate binding of cilia-targeted proteins to membranes to allow for their delivery to the cilium, or (b) facilitate interactions with specific chaperones that deliver proteins to the cilium
- Structure of the ciliary tip central pair reveals the unique . . .
Motile cilia are unique organelles with the ability to autonomously move Force generated by beating cilia propels cells and moves fluids The ciliary skeleton is made of peripheral doublet microtubules and a central pair (CP) with a distinct
- Primary Ciliary Signaling in the Skin—Contribution to Wound . . .
Basic components and rough characteristics of each indicated signaling pathway in relation to primary cilia (A) TGFbeta receptors accumulate in the primary cilia, and ligand binding to the TGFBR2 faciliates recruitment of TGFBR1 to form the heterodimeric receptor complex Subsequent phosphorylation and activation of the receptor leads to downstream activation of the SMAD family of
|
|
|