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- Cisplatin - MilliporeSigma
Cisplatin, Cisplatin - CAS 15663-27-1, is a platinum coordination complex with potent anti-neoplastic activity Induces apoptosis in cancer cells, possibly via caspase-3 activation
- Protein-bound cisplatin could exhibit an efficient antitumor effect in . . .
Cisplatin, that is 300 05 Da, is a platinum-based anticancer agent Its mechanism of action to induce cytotoxicity is primarily to arrest the cell-division cycle via interaction with the guanine bases in nuclear DNA, which induces partial breaks in double-strand DNA 1 that then promote interruptions in transcription and cellular replication 2 Cisplatin was approved by the US Food and Drug
- ONC201 enhances the cytotoxic effect of cisplatin through ATF3 ATF4 . . .
A cisplatin-resistant HNSCC subline (OC2-CR1) was developed via long-term drug exposure The treatment effectiveness of ONC201 alone and cisplatin in combination on cell viability, DNA damage
- Overcoming cisplatin resistance via deep learning-assisted de novo . . .
Resistance to cisplatin poses a significant challenge in cancer treatment for patients globally Despite the continuous efforts of both the pharmaceutical industry and academia, no new platinum drugs have been approved for the treatment of cancers that have developed resistance to cisplatin-based chemotherapy regimens Even in the new era of AI, the potential to accelerate the discovery of
- Treatment with gemcitabine cisplatin and durvalumab for advanced . . .
The addition of the anti-programmed cell death-ligand 1 (anti-PD-L1) antibody durvalumab to the established first-line palliative therapy with gemcitabine cisplatin significantly extended median overall survival (mOS) to 12 8 months (95% CI, 11 1 to 14 0) compared to 11 5 months in patients treated with gemcitabine cisplatin (95% CI, 10 1 to 12 5)
- Cisplatin Uses, Side Effects Warnings - Drugs. com
Cisplatin: side effects, dosage, interactions, FAQs, reviews Used for: anal cancer, bladder cancer, blood cell transplantation, bone marrow transplantation, brain tumor, and more Skip to main content
- Cisplatin - Wikipedia
Cisplatin is a chemical compound with formula cis-[Pt(NH 3) 2 Cl 2] It is a coordination complex of platinum that is used as a chemotherapy medication used to treat a number of cancers [2]
- Cisplatin - NCI - National Cancer Institute
Cisplatin is a type of chemotherapy drug called an alkylating agent It contains the metal platinum, which binds to and damages the cell’s DNA, preventing it from being repaired or copied This stops cells from dividing and causes them to die
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