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- Cytokine - Wikipedia
The effect of a particular cytokine on a given cell depends on the cytokine, its extracellular abundance, the presence and abundance of the complementary receptor on the cell surface, and downstream signals activated by receptor binding; these last two factors can vary by cell type
- What are Cytokines? Types Function - Cleveland Clinic
Think of a cytokine as a key and the receptor on the receiving cell like a lock When the cytokine (key) enters the cytokine receptor (lock), the receiving cell receives a message that tells it what to do
- What Are Cytokines? Types, Function, and Immunity
One cytokine might stimulate growth in one cell type while triggering inflammation in another Multiple cytokines also work in concert, layering their signals to fine-tune the immune response
- What Are Cytokines and How Do They Signal Immune Responses?
The term “cytokine” refers to a broad class of molecules, including interleukins, interferons, tumor necrosis factors, colony-stimulating factors, chemokines, and growth factors
- Cytokines: Introduction | British Society for Immunology
This action may occur in an autocrine (acts on same cell), paracrine (acts on nearby cell) or endocrine (acts on distant cell; not the normal manner for cytokine responses) manner
- Cytokine - an overview | ScienceDirect Topics
A key aspect of cytokine biology is that an individual cytokine can elicit varying responses in many different types of cells This pleiotropic property is amplified by cytokine redundancy
- Understanding cytokines and their role in the immune system
Cytokine storm, or cytokine release syndrome (CRS) in severe COVID-19 cases results from a dysregulated immune response, marked by delayed production of type-I and type-III IFNs and a subsequent surge in proinflammatory cytokines such as IL-6, IL-8, and TNFα 80
- Cytokines - PMC
The cytokine shows a different biological activity spectrum, in particular in its action of differentiating normal and B lymphocytes, and as an immunomodulator of macrophage activity It also has an important role in dealing with intracellular pathogens, including viruses, and tumor control
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