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- DAMPS(损伤相关的分子模式)_百度百科
损伤相关的分子模式(DAMPs)是细胞因损伤或应激产生的内源性危险信号分子,当机体遭受损伤、缺氧等刺激后,其分布、浓度或理化性质发生改变,从而被Toll样受体、RIG-I样受体、NLRP3等模式识别受体识别。
- 损伤相关分子模式 - 维基百科,自由的百科全书
^ 7 0 7 1 Rubartelli A, Lotze MT Inside, outside, upside down: damage-associated molecular-pattern molecules (DAMPs) and redox Trends in Immunology October 2007, 28 (10): 429–36 PMID 17845865 doi:10 1016 j it 2007 08 004 ^ Gong, Tao; Liu, Lei; Jiang, Wei; Zhou, Rongbin DAMP-sensing receptors in sterile inflammation and inflammatory
- DAMPs and DAMP-sensing receptors in inflammation and diseases
Summary Damage-associated molecular patterns (DAMPs) are endogenous danger molecules produced in cellular damage or stress, and they can activate the innate immune system DAMPs contain multiple types of molecules, including nucleic acids, proteins, ions, glycans, and metabolites
- 中国科大在Immunity杂志30周年特刊发表综述总结DAMPs与无菌性炎症领域研究进展
近年来的研究发现DAMPs及其介导的炎症反应在多种重大慢性疾病的发生发展中起关键作用。 因此,对DAMPs及其诱导的炎症反应的深入理解不仅有助于揭示免疫应答的本质,也有助于发展新的免疫疗法。
- DAMP sensing and sterile inflammation: intracellular . . . - Nature
Damage-associated molecular patterns (DAMPs) are endogenous molecules that are released from host cells as a result of cell death or damage
- The Role of Damage-Associated Molecular Patterns (DAMPs) in Human . . .
This article is the second part of a review that addresses the role of damage-associated molecular patterns (DAMPs) in human diseases by presenting examples of traumatic (systemic inflammatory response syndrome), cardiovascular (myocardial
- Damage-associated molecular pattern - Wikipedia
DAMPs vary greatly depending on the type of cell (epithelial or mesenchymal) and injured tissue, but they all share the common feature of stimulating an innate immune response within an organism
- Damage-associated molecular patterns | Review | InvivoGen
Damage-associated molecular patterns (DAMPs), also known as alarmins, are molecules released by stressed cells undergoing necrosis that act as endogenous danger signals to promote and exacerbate the inflammatory response
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