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- HCT116 Cell Line: A Pillar in Colorectal Cancer Research
The HCT116 colon cancer cell line is used to study colon cancer progression and development Moreover, it helps enlighten the underlying mechanisms and signaling pathways involved in cancer proliferation, migration, and invasion A study used HCT116 cells to study genes involved in drug resistance development
- Characteristics of the HCT116 Cell Line Explained - mindovix. com
The HCT116 cell line is more than just a standard tool in the cancer research toolkit; it sits at the crossroads of genetics and experimental pathology Understanding its unique characteristics can provide researchers with invaluable insights into the complexities of carcinoma, particularly colorectal cancer
- Maintenance of HCT116 colon cancer cell line conforms to a . . .
The existence of cancer stem cells (CSCs) in human primary solid tumors, such as glioblastoma, and breast, colon, and hematopoietic tumors, has been confirmed through the use of techniques such as cell fractionation, which is based on the expression of CSC‐specific markers, and xenotransplantation
- HCT116 cells - Wikipedia
HCT116 cells are used in a variety of biomedical studies involving colon cancer proliferation and corresponding inhibitors The cell line has been used in tumorigenicity studies, along with other research that has shown that Cyclin D1 holds large importance for the activity of lithocholic acid hydroxyamide
- HCT 116 Cell Line
The mechanistic studies in human colon cancer cell line revealed that HCT116 cell line is highly sensitive to 45 which demonstrated remarkable tumour inhibitory potential The compound 45 did not affect the growth of normal cells and exhibited GI 50 value of 3 57 ± 0 45 µM The compound was also observed to generate a huge number of sub-G1
- Characterization of HCT116 human colon cancer cells in an . . .
In the absence of any transgenic models of colon cancer metastases, an in vivo model system that fulfills the rate limiting steps of metastasis (local invasion and distant colony formation) is needed The purpose of this study was to characterize the behavior of a human colon cancer cell line, HCT116 in an orthotopic model
- HCT 116 - CCL-247 - ATCC
HCT 116 is an adherent cell line isolated from the colon of a patient with colon cancer It has a mutation in codon 13 of the ras-proto-oncogene This cell line is near-diploid and has a relatively stable genetic profile, making it a valuable in vitro model This line can be utilized in cancer research and gastrointestinal (GI) research
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