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- MAPK ERK pathway - Wikipedia
The MAPK ERK pathway (also known as the Ras-Raf-MEK-ERK pathway) is a chain of proteins in the cell that communicates a signal from a receptor on the surface of the cell to the DNA in the nucleus of the cell
- ERK signalling: a master regulator of cell behaviour, life and fate
By phosphorylating widely diverse substrates, ERK proteins govern a variety of evolutionarily conserved cellular processes in metazoans, the dysregulation of which contributes to the cause of
- ERK MAPK signalling pathway and tumorigenesis - PMC
Extracellular signal-regulated kinase 1 2 (ERK) belongs to the mitogen-activated protein kinase (MAPK) family, which plays a role in signalling cascades and transmits extracellular signals to intracellular targets
- Erk Signaling Pathway - Creative Diagnostics
The ERK signaling pathway plays a role in several steps of tumor development The phosphorylation by ERK of proteins such as myosin light chain kinase, calpain, focal adhesion kinase, and paxillin promotes cancer cell migration
- ERK1 2 MAP kinases: structure, function, and regulation
ERK1 2 are proline-directed kinases that preferentially catalyze the phosphorylation of substrates containing a Pro-Xxx-Ser Thr-Pro sequence Besides this primary structure requirement, many ERK1 2 substrates possess a D-docking site, an F-docking site, or both
- Extracellular Signal-Regulated Kinases: One Pathway, Multiple Fates - MDPI
The ERK pathway is a key cell signaling system activated by physiological factors or oncogenic mutations, influencing different cell outcomes The protein kinases ERK1 and ERK2 (ERK) acting at the end of the pathway control whether cells grow, differentiate, age, or die
- Extracellular Signal-Regulated Kinase: A Regulator of Cell Growth . . .
Extracellular signal-regulated kinase (ERK) is a member of the mitogen-activated protein kinase family of signaling molecules ERK is predominantly found in two forms, ERK1 (p44) and ERK2 (p42), respectively There are also several atypical forms of ERK, including ERK3, ERK4, ERK5 and ERK7
- The ERK Signal Transduction Pathway - R D Systems
Read our article on The ERK Signal Transduction Pathway and its role in growth factor signaling and cancer
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