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- Mechanism of cocaine-induced hyperthermia in humans
When healthy, cocaine-naive persons are subjected to passive heating, pretreatment with even a small dose of intranasal cocaine impairs sweating and cutaneous vasodilation (the major autonomic adjustments to thermal stress) and heat perception (the key trigger for behavioral adjustments)
- Cocaine - Veterans Affairs
Injecting or smoking cocaine produces a quicker, stronger high than snorting On the other hand, faster absorption usually means shorter duration of action: the high from snorting cocaine may last 15 to 30 minutes, but the high from smoking may last only 5 to 10 minutes
- Short- Long-Term Effects of Crack Cocaine - Recovery. org
The term “crack” refers to cocaine that has been processed with baking soda or ammonia, water, and heat to produce a “rock” form that can be smoked 1 Cocaine produces fast-acting effects; however, they are short-lived and typically last for just a few minutes 1, 2 Smoking crack cocaine results in a faster onset of effects, is
- How Is Crack Different From Cocaine? | Key Differences Explained
How do the effects of crack differ from those of cocaine? Crack produces a much more intense high due to its method of consumption, which allows for quicker absorption Users experience peak effects within seconds when smoking crack, compared to several minutes for powder cocaine
- Crack Cocaine 101: What Is “Crack” and How Does It Affect the . . .
The chemical structure of crack cocaine allows it to cross the blood-brain barrier rapidly, creating intense effects within seconds This quick-acting nature stems from its altered molecular form, making it more potent than powder cocaine
- Why is smoked cocaine (crack) more likely to be abused or . . .
Cocaine produces its high within seconds when smoked as crack; but it takes several minutes to produce a high when snorted (see Figure 5) Furthermore, cocaine leaves the brain very quickly after smoking stops, so the cocaine high produced by smoking does not last very long
- Cocaine Toxicity • LITFL • CCC Toxicology
Cocaine hydrochloride powder or paste: processed from the alkaloid extracted from cocoa leaves, it cannot be smoked as it decomposes at high temperatures; Cocaine base (crack cocaine) or free-base: created by combining cocaine hydrochloride with an alkaline substance, it is heat stable RISK ASSESSMENT toxic dose is highly variable
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