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- Chapter 45 Practice Flashcards - Quizlet
Lipid-insoluble hormones affect their target cells by binding to receptors inside the cell Lipid-insoluble hormones cannot cross the plasma membrane and get into the cell, so they must bind to receptors on the cell surface and transduce their signals through signal transduction pathways
- Openstax Biology Chapter 9 Flashcards - Quizlet
Can directly diffuse through the plasma membrane and interact with internal receptors Most important ligand is the steroids including estradiol (estrogen), testosterone and cholesterol
- Chapter 16 - Cell signaling Flashcards - Quizlet
Upon GPCR activation, GEF exchanges GDP for GTP on the α subunit The α subunit and βγ complex, dissociate to interact with their preferred target proteins in the plasma membrane The receptor stays active as long as the external signal molecule is bound to it, and it can therefore activate many molecules of G protein
- Signaling Molecules and Cellular Receptors - OpenEd CUNY
Hydrophobic signaling molecules typically diffuse across the plasma membrane and interact with intracellular receptors in the cytoplasm Many intracellular receptors are transcription factors that interact with DNA in the nucleus and regulate gene expression
- 9. 4: Signaling Molecules and Cellular Receptors - Biology LibreTexts
Hydrophobic signaling molecules ( ligands ) can diffuse through the plasma membrane and bind to internal receptors Water-soluble ligands are unable to pass freely through the plasma membrane due to their polarity and must bind to an extracellular domain of a cell -surface receptor
- Chapter 11 Flashcards - Quizlet
Cortisol is a small, hydrophobic steroid hormone that can pass through the plasma membrane of cells In target cells, cortisol binds to the intracellular receptor protein in the cytoplasm, forming a hormone-receptor complex
- Signaling Molecules and Cellular Receptors – Biology - UH Pressbooks
Hydrophobic signaling molecules typically diffuse across the plasma membrane and interact with intracellular receptors in the cytoplasm Many intracellular receptors are transcription factors that interact with DNA in the nucleus and regulate gene expression
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