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- Integrin - Wikipedia
Integrin subunits span the cell membrane and have short cytoplasmic domains of 40–70 amino acids The exception is the beta-4 subunit, which has a cytoplasmic domain of 1,088 amino acids, one of the largest of any membrane protein
- What Is Integrin? Structure, Function, and Disease
When an integrin binds to a molecule outside the cell, it triggers chemical signals that tell the cell where it is, what type of tissue surrounds it, and whether it should move, divide, or stay put
- Integrins in Health and Disease | NEJM - New England Journal of Medicine
Dr Hynes coined the term “integrin” for these wonderfully complicated molecules that “integrate” the extracellular matrix with the intracellular environment (the cytoskeleton, in particular)
- Definition of integrin - NCI Dictionary of Cancer Terms
integrin (IN-teh-grin) A type of protein found on the surface of cells that helps them attach to, and communicate with, nearby cells Integrins also help cells attach to large molecules in the extracellular matrix, the substance that surrounds and gives structure to cells
- Integrin - an overview | ScienceDirect Topics
We highlight the role of integrins in regulating tumor metastasis, immune evasion, metabolic reprogramming, and other hallmarks of cancer In addition, integrin-targeted immunotherapy and other integrin inhibitors used in preclinical and clinical studies are summarized
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