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- JMJD6 Gene - GeneCards | JMJD6 Protein | JMJD6 Antibody
JMJD6 (Jumonji Domain Containing 6, Arginine Demethylase And Lysine Hydroxylase) is a Protein Coding gene Diseases associated with JMJD6 include Pontocerebellar Hypoplasia, Type 2F and Pancreatitis Among its related pathways are Metabolism of proteins and Chromatin organization
- Targeting JMJD6: A Novel Approach in Cancer Therapy?
JMJD6 plays an important role in transcriptional regulation, RNA splicing, inflammation, and immune responses It downregulates pathways and activities like p53, TGF-β signaling, and Myc-induced apoptosis, while upregulating processes such as CDKs, WNT, MAPK, and autophagy pathways
- Role of the Epigenetic Modifier JMJD6 in Tumor Development and . . .
JMJD6 is a member of the Jumonji (JMJC) domain family of histone demethylases that contributes to catalyzing the demethylation of H3R2me2 and or H4R3me2 and regulating the expression of specific genes JMJD6-mediated demethylation modifications are involved in the regulation of transcription, chromatin structure, epigenetics, and genome integrity
- JMJD6 Shapes a Pro-tumor Microenvironment via ANXA1-Dependent . . .
Jumonji domain-containing 6 (JMJD6) is an epigenetic regulator which demethylates arginine and hydroxylates lysine on both histone and nonhistone proteins, including ERα (7) Expression of JMJD6 has been linked to progression and poor prognosis of several tumor types, including oral cancer (8), colon cancer (9), and hepatocellular carcinoma (10)
- JMJD6 Autoantibodies as a Potential Biomarker for Inflammation . . . - MDPI
In this study, Jumonji C-domain-containing 6 (JMJD6) was identified by the serological identification of antigens through recombinant cDNA expression cloning In particular, JMJD6 is an antigen recognized in serum IgG from patients with unstable angina pectoris (a cardiovascular disease)
- ChIPAb+ JMJD6 - ChIP Validated Antibody and Primer Set
JMJD6 is a critical component of embryogenesis for the differentiation of various organs, and may act as a regulator for hematopoietic regulation and macrophage cytokine response High expression of JMJD6 has been observed in heart, kidney and skeletal muscle
- Cancer Res | 张传杰 高轶 徐丹枫等论述前列腺癌JMJD6驱动AR非依赖全新铁死亡防御机制
高表达JMJD6通过与ATF4形成表观复合物，且独立于BRD4 AR，劫持并重塑谷胱甘肽合成关键酶基因增强子，促进肿瘤细胞胱氨酸吸收及谷胱甘肽代谢成瘾，导致该类前列腺癌亚群天然铁死亡耐受。
- Jumonji domain-containing 6 (JMJD6) identified as a potential . . .
Jumonji domain-containing 6 (JMJD6) is a candidate gene associated with tumorigenesis, and JMJD6 overexpression predicts poor differentiation and unfavorable survival in some cancers
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