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- KRAS - Wikipedia
KRAS (Kirsten rat sarcoma virus) is a gene that provides instructions for making a protein called K-Ras, a part of the RAS MAPK pathway The protein relays signals from outside the cell to the cell's nucleus
- What’s new in KRAS mutation research? - MD Anderson Cancer Center
The most frequently mutated of these oncogenic driver genes, called KRAS, is associated with some of the most fatal cancer types: lung, pancreatic and colorectal cancers
- KRAS gene - MedlinePlus
The KRAS gene provides instructions for making a protein called K-Ras that is part of a signaling pathway known as the RAS MAPK pathway The protein relays signals from outside the cell to the cell's nucleus
- KRAS mutation: from undruggable to druggable in cancer
As the most frequently mutated oncogene, Kirsten rat sarcoma viral oncogene homologue (KRAS) has attracted substantial attention The understanding of KRAS is constantly being updated by numerous
- KRAS Mutations in Solid Tumors: Characteristics, Current Therapeutic . . .
Kristen rat sarcoma (KRAS) gene is one of the most common mutated oncogenes in solid tumors Yet, KRAS inhibitors did not follow suit with the development of targeted therapy, for the structure of KRAS has been considered as being implausible to target for decades
- KRAS Oncoprotein Signaling in Cancer | New England Journal of Medicine
Recent studies provide new insights into signaling by mutant KRAS, inhibitors of which have provided modest benefits for patients
- Uniquely engineered KRAS-targeted cancer drug found to be effective in . . .
Some KRAS mutations occur at a higher frequency in certain cancer subtypes: the G12V mutation is a common KRAS mutation amongst lung (22%), colon (22%) and pancreatic (30%) cancers Starting in the lab, the researchers set out to identify a promising cell surface receptor that could selectively deliver their RNA molecules into the tumor cells
- What is KRAS Cancer
KRAS is the most common biomarker associated with lung, colorectal, pancreatic plus other cancers Identified 50 years ago, researchers have learned that different sub-types of KRAS respond to treatments differently
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