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- Tricyclic 2-Deoxycytidine Analogs: Syntheses and Incorporation into . . .
A cytosine analog that confers enhanced potency to antisense oligonucleotides Proceedings of the National Academy of Sciences 1999, 96 (7) , 3513-3518 https: doi org 10 1073 pnas 96 7 3513
- Glen Report 22. 13: tC, tCo and tCnitro: Tricyclic Cytosine Probes of . . .
Now, with technical and scientific support from ModyBase HB, we have added to our catalog two new fluorescent base analogues, tC and tC O (Figure 1), which are virtually insensitive to their microenvironment
- Functionalized Tricyclic Cytosine Analogues Provide Nucleoside . . .
Tricyclic cytosines (tC and tC O frameworks) have emerged as a unique class of fluorescent nucleobase analogues that minimally perturb the structure of B-form DNA and that are not quenched in duplex nucleic acids
- Photophysical and structural properties of the fluorescent nucleobase . . .
30 flexible tricyclic frameworks of all of the tC bases predicted here help explain their properties in nucleic acid contexts as well as their ability to adapt to different kinds of confined (biological) environments such as various nucleic acid scenarios and in protein binding pockets
- Nucleoside analogue - Wikipedia
There are, however, several different nucleoside analogue drugs and resistance to one of them is usually overcome by switching to another drug of the same kind (e g famciclovir, penciclovir, valaciclovir)
- tCo tricyclic dC - Gene Link
The base analogue tCnitro is a FRET-acceptor together with tCO (or tC) as the donor molecule This constitutes the first ever description of a nucleobase FRET-pair
- Pyrimidine Antagonist - an overview | ScienceDirect Topics
Pyrimidine antagonists are structural analogs of pyrimidine nucleotides such as cytosine, uracil, and thiamine The main drugs belonging to this category are 5-fluorouracil, cytarabine, and gemcitabine, and these are widely used in chemotherapy regimens against colorectal, breast, head and neck, NSCLC, pancreatic cancer, and leukemia
- Functionalized tricyclic cytosine analogues provide nucleoside . . .
Tricyclic cytosines (tC and tC (O) frameworks) have emerged as a unique class of fluorescent nucleobase analogues that minimally perturb the structure of B-form DNA and that are not quenched in duplex nucleic acids
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