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- Regeneration of zebrafish retina following toxic injury
The structure of the zebrafish retina appears to be very similar to that of mammals, that is why it is used as a model for studying the eye Indeed, the zebrafish retina can regenerate itself through mechanisms of Müller cell reprogramming In this research, adult zebrafish were exposed to aluminum to cause damage in the retina and thus evaluate the regenerative capacity of the damaged tissue
- The Zebrafish as a Model for Ocular Translational Research . . .
Overview of present and potential zebrafish applications in basic, applied, and translational Zebrafish eye research Retinogenesis and regeneration upon physiological and pathological states represent the major fields of investigation in zebrafish model
- Regenerative Properties of Zebrafish Used for Treating . . .
The tiny zebrafish may hold the key to slowing or even reversing eye diseases that affect millions of people, especially our aging population The reason for this is that zebrafish, unlike mammals, are able to regenerate an injured or diseased retina Understanding how zebrafish accomplish this amazing feat may suggest novel strategies for stimulating retinal repair in mammals The laboratory
- Could a tiny fish hold the key to curing blindness?
Patton’s findings help identify cues that stimulate zebrafish regeneration Jeff Mumm, Johns Hopkins University, reported that immune cells in the retina called microglia are necessary for zebrafish Müller glia to initiate regeneration after injury
- Are zebrafish good for your eyes? - The Institute for . . .
Are Zebrafish Good for Your Eyes? Unveiling the Science Behind Retinal Regeneration While zebrafish can’t directly improve your vision in the way glasses or surgery can, their remarkable ability to regenerate retinal tissue offers invaluable insights and holds immense promise for future treatments for human eye diseases
- Optimized in vivo two-photon imaging reveals the essential . . .
Background The visual pathway, consisting of the eye, optic nerve, and brain, serves as a valuable model for studying neural regeneration The exceptional regenerative capacity of the zebrafish visual system enables detailed investigation of neural repair mechanisms in vivo Although the transparency of zebrafish larvae permits real-time imaging of axonal regeneration following transection
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