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- Forcing Loperamide through the BBB | Bluelight. org
There's a thread by TheTripDoctor on Loperamide in Other Drugs, it seems that he found the way to enjoy Loperamide In the thread, it has been said that the way to feel an effect from Loperamide is to take a very large amount of it (just like GABA doesn't cross the BBB, but is taken in 1 to 5 grams doses, so a part of it goes through the BBB)
- Regular recreational use of loperamide. - Bluelight. org
I dose 100mg of loperamide, 50 2mg tablets, along with 2-3 tablespoons of black pepper and 25mg benadryl The black pepper has piperine which supposedly helps it cross the BBB, and the benadryl is necessary because without it I become very nauseous and itchy
- Forcing Loperamide through the BBB | Page 6 | Bluelight. org
Loperamide has a 2-phase dose response curve, has roughly 1 40th of the mu affinity of codeine and the specific dose at which the ABC binding cassette is overcome and the drug reaches it's second phase dose-response Loperamide is an extreme example of a compound removed from the brain by Pgp efflux (efflux ratios ranging from 6 5 to 9 9)
- How I kicked opiates by using loperamide - my story.
But seriously, loperamide can fuck up your heart if you take to much, which it sounds like you did (for years) Severe cardiac arrhythmias including QTc prolongation can happen when you overtake loperamide Today, loperamide holds a Black Box Warning for reports of Torsades de Pointes and sudden death when used in higher than recommended doses
- Opioids Loperamide+Tagamet dosing guidance needed
Better yet you should start tapering ASAP The fortunately thing about loperamide is that its easy to taper by just a single milligram, so it should be a pretty smooth taper I once had a 100mg a day due to its use as an detox tool and was able to taper off The insomnia is pretty intense with loperamide withdrawal though
- The Reality Of A Loperamide Overdose - Bluelight. org
As a quick summary - Loperamide is a potent opioid that cannot pass the blood brain barrier in therapeutic doses (it does attach to GI opioid receptors slowing GI movement) It turns out this man got far more than he bargained for and did not heed the warnings of cardiotoxicity and remained complacent in the face of an ultimatum: go through the
- Opioids How much Loperamide. . . - Bluelight. org
Loperamide is slow to take effect (and slow to metabolize, people get in trouble with doing every day because its absolute floor half life of 11h-- possibly much higher for larger doses-- means constantly escalating levels)
- Opioids - Loperamide (Imodium) Megathread v. 2 | Bluelight. org
Loperamide is an opioid drug used against diarrhea resulting from gastroenteritis or inflammatory bowel disease In most countries it is available generically and under brand names such as Lopex, Imodium, Dimor, Fortasec, Lopedium, Gastro-Stop and Pepto Diarrhea Control
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