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  • Elective high frequency ventilation compared to conventional . . .
    Does the elective use of high frequency oscillatory ventilation as compared to conventional ventilation reduce lung damage and other complications associated with prematurity and assisted ventilation in preterm infants who are mechanically ventilated for respiratory distress syndrome (RDS)?
  • Elective high frequency oscillatory ventilation versus . . .
    Main results: Nineteen eligible studies involving 4096 infants were included Meta-analysis comparing HFOV with CV revealed no evidence of effect on mortality at 28 to 30 days of age or at approximately term equivalent age These results were consistent across studies and in subgroup analyses
  • Elective high frequency jet ventilation versus conventional . . .
    The objective of this review was to determine whether the elective use of high frequency jet ventilation (HFJV) as compared to conventional ventilation in preterm infants with RDS who were mechanically ventilated would decrease the incidence of chronic lung disease without adverse effects
  • Cochrane review: Elective high frequency oscillatory . . .
    Insufficient evidence exists to support the routine use of high frequency oscillatory ventilation (HFOV) instead of conventional ventilation for preterm infants with lung disease who are given positive pressure ventilation
  • Elective high-frequency oscillatory versus conventional . . .
    For infants ventilated with HFOV, the relative risk of death or bronchopulmonary dysplasia at 36 weeks' postmenstrual age was 0·95 (95% CI 0·88–1·03), of death or severe adverse neurological event 1·00 (0·88–1·13), or any of these outcomes 0·98 (0·91–1·05)
  • Elective High-Frequency Oscillatory Ventilation versus . . .
    Future trials on elective HFOV should target those infants who are at most risk of CLD (extremely preterm infants), compare different strategies for generating HFOV and CV, and report important long-term neurodevelopmen-tal outcomes


















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