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- Mitochondrial Gene - an overview | ScienceDirect Topics
A high level of mitochondrial DNA sequence variation was observed in nasopharyngeal carcinoma patients who later developed moderate to severe deep tissue fibrosis as a late complication of radiation therapy In contrast, the patients with no or minimal fibrotic reactions were those with low levels of mitochondrial DNA sequence variations [69]
- Mechanisms of mammalian mitochondrial transcription - PMC
The mitochondrial ribosomal protein L12 (MRPL12) seems to be a positive regulator of the mitochondrial transcription process by controlling POLRMT stability 121 MRPL12 expression correlates with the steady‐state levels of mitochondrial transcripts 122, 123 There is growing evidence suggesting that mitochondrial transcription is also regulated
- Animal Mitochondrial DNA: Structure and Evolution
Because in mammals and amphibia, this sequence has been shown to include the signals necessary for the initiation of H-strand synthesis (that is, the molecule's replication origin), and for both H-strand and L-strand transcription (Montoya et al , 1982, 1983; Clayton, 1984), it has been designated the control region
- Whole-genome phylogeny of mammals: Evolutionary . . . - PNAS
We partitioned the complete genomes of mammals (such as human, chimp, horse, and mouse) into their constituent nongenic, intronic, and exonic components Phylogenic species trees were constructed for each individual component class of genome sequence data as well as the whole genomes by using standard tree-building algorithms with FFP distances
- Rapid mitochondrial genome sequencing based on Oxford . . .
By prefiltering the mitochondrial DNA sequences (from the total sequenced genomic DNA), our method saves computing time while it also improves the ability of the method to positively identify the species since multiple mitochondrial loci are available in public databases for many metazoan specimens (opposed to the comparatively low availability
- Updating the 97% identity threshold for 16S ribosomal RNA . . .
Sequences are often clustered into Operational Taxonomic Units (OTUs) as proxies for species The canonical clustering threshold is 97% identity, which was proposed in 1994 when few 16S rRNA sequences were available, motivating a reassessment on current data
- Factors Affecting the Relative Abundance of Nuclear Copies of . . .
Although nuclear copies of mitochondrial DNA (numts) can originate from any portion of the mitochondrial genome, evidence from humans suggests that more variable parts of the mitochondrial genome, such as the mitochondrial control region (MCR), are under-represented in the nucleus This apparent deficit might arise from the erosion of sequence identity in numts originating from rapidly
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