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- Organoids: A new window into disease, development and discovery
Organoids are tiny, self-organized three-dimensional tissue cultures that are derived from stem cells Such cultures can be crafted to replicate much of the complexity of an organ, or to express selected aspects of it like producing only certain types of cells
- What Is an Organoid? - ScienceAlert
Organoids are small, simplified, 3D copies of organs created outside of a living body, usually grown by treating combinations of tissues or stem cells with the nutrients and chemical signals (growth factors) that encourage them to differentiate and self-organize
- Organoids: The current status and biomedical applications
Organoid technologies pave the way for the development of new models that more closely resemble realistic physiological and pathophysiological states In this review, we introduced the development and current advances in the field of organoids and described the main cell sources and culture methods for organoids
- Organoids - PubMed
Organoids are derived from either pluripotent or tissue-resident stem (embryonic or adult) or progenitor or differentiated cells from healthy or diseased tissues, such as tumors To date, numerous organoid engineering strategies that support organoid culture and growth, proliferation, differentiation and maturation have been reported
- Roche | Mapping the future of organoids
Without the organoid atlases, this comparison wasn’t possible The atlases will also be critical to enable the deployment of organoids in the drug development context For example, this rich organoid resource can serve as a complex, diverse control for identifying new therapeutic targets
- Human organoids: model systems for human biology and medicine
Human organoids have been used to study infectious diseases, genetic disorders and cancers through the genetic engineering of human stem cells, as well as directly when organoids are generated
- Landscape of human organoids: Ideal model in clinics and research
The landscape of organoids history: organoids mark a new and efficient model in tissue and organ level Multiple applications of organoids in biomedicine and life healthcare Organoids bene t to drug discovery, disease study, prevention, control, and therapy
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